Senior Research Scientist

hace 5 días


Tarragona, Tarragona, España Barcelona Institute Of Science And Technology (Bist) A tiempo completo

The Barcelona Institute of Science and Technology (BIST) seeks a highly skilled Senior Research Scientist to join the Suero research group. This position will be funded by the European Research Council - ERC Proof of Concept project Cyclo-warhead.

At BIST, we are committed to solving major social and economic challenges through top-quality research in sustainable catalysis, renewable energy, and health. We aim to train the next generation of scientists through high-quality educational programs for master, PhD students, and postdoctoral researchers.

Description of the Project

Over the past two decades, the pharmaceutical industry has witnessed an exponential growth in approved covalent drugs. The majority of such drugs incorporate a chemical warhead, a mild electrophilic reactive functional group that forms covalent bonds in a reversible or irreversible manner with nucleophilic amino acid residues. During the first 18 months of this position, the candidate will assess the viability of new chemical warheads in the discovery of novel kinase inhibitors. The project will involve the use of reagents suitable for late-stage functionalization. In the last 18 months, the project will involve the discovery and development of novel skeletal editing platforms to impact medicinal chemistry.

Responsibilities

  • Design and discovery of novel kinase inhibitors with new chemical warheads.
  • Writing reports, preparation of scientific articles, and presentation of results in group meetings and conferences.
  • Complete documentation of research results.

Requirements

A PhD in Organic Chemistry is required. The ideal candidate should have a proven track record in chemical synthesis, catalysis, and medicinal chemistry. Strong written and spoken English skills are essential. A strong commitment to scientific excellence is expected.

We Offer

A 3-year full-time contract is available, with remuneration according to individual qualification and experience. The annual salary is estimated at €60,000 per year, split into twelve monthly payments. This position will commence in January 2025.

About ICIQ

The Institute of Chemical Research of Catalonia (ICIQ) is one of the world's leading institutions in the field of chemistry, dedicated to solving major social and economic challenges. We strive to conduct top-quality research in three main areas: sustainable catalysis, renewable energy, and health.



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