Postdoctoral Research Assistant for Computational Oncology Group

hace 2 días

Barcelona, Barcelona, España Cnio A tiempo completo
Join Our Team as a Postdoctoral Research Assistant

We are seeking a highly motivated and experienced postdoctoral researcher to join our team at the Spanish National Cancer Centre (CNIO) in Madrid, Spain. As a postdoctoral research assistant, you will work closely with our team to develop computational approaches to help guide the chemoprevention of cancer.

About the Project

Our team is part of the Computational Oncology Group, led by Dr. Geoff Macintyre, and we are working on developing innovative computational algorithms to dissect different types of chromosomal instability (CIN) in tumours. We have recently pioneered an algorithm capable of predicting response to existing therapies, and we are now looking to adapt our methods to decompose patterns of CIN at an unprecedented resolution and at different timepoints of tumour evolution.

Your Role

As a postdoctoral research assistant, you will be responsible for developing new AI methodologies to process sequencing data from >50,000 tumour genomes, reformulating features to encode patterns of copy number changes at base-pair resolution, and decomposing CIN in the new feature space by applying deep-learning approaches. You will also characterise these signatures by integrating orthogonal data and design a web-based tool for leveraging these advances.

Requirements
  • PhD degree in bioinformatics, computational biology, computer science, mathematics, physics, or statistics
  • Proven expertise in bioinformatics, particularly in cancer genomics, tumour evolution, and mutational signature analysis
  • Experience in analysing whole genome sequence data
  • Coding experience (preferably in R and Python)
  • Experience with high performance and/or cloud computing
  • Manuscript writing
  • English proficiency
What We Offer

We offer a competitive salary, social benefits, and a contract linked to a project. You will also have the opportunity to work in a Cancer Research Centre of excellence of international relevance and contribute to the development of innovative computational approaches to help guide the chemoprevention of cancer.

Apply now to join our team and be part of this exciting project

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