Senior Research Scientist in Neurodegenerative Diseases

hace 1 semana


Barcelona, Barcelona, España Université Du Luxembourg A tiempo completo

The Université du Luxembourg is a dynamic and innovative university with a strong focus on research and education. Our mission is to foster a spirit of curiosity and creativity, and to provide our students and researchers with the ideal environment to develop their skills and expertise.

We are seeking a highly motivated and experienced researcher to join our team at the Luxembourg Centre for Systems Biomedicine (LCSB). As a Senior Research Scientist in Neurodegenerative Diseases, you will be working on a 21-month project funded by the FNR and in collaboration with Accure Therapeutics, to investigate the cellular and molecular alterations underlying Parkinson's disease pathogenesis. The goal of this project is to understand the role of Prolyl Endopeptidase (PREP) enzyme in PD and to identify potential therapeutic targets for the treatment of this devastating disease.

Your main responsibilities will include:
1. Conducting extensive experimental work, including cellular (neuronal differentiation, drug treatment) and molecular/functional analyses (assessment of mitochondrial and lysosomal function, investigation of intracellular signaling pathways, evaluation of dopaminergic neurons activity and viability)
2. Collaborating with international partners to validate relevant findings in corresponding PD mouse models
3. Dissecting the contribution of PREP to PD pathogenesis and identifying potential PD patient subgroups eligible for future ACT-02 clinical trials

To succeed in this role, you will need to have a PhD in Neurosciences, Cell Biology or related fields, and extensive experience in working with cell-based models and mastering cellular/molecular biology and biochemistry techniques. You will also need to be highly motivated and enthusiastic, with excellent communication and teamwork skills.

This position offers a unique opportunity to contribute to cutting-edge research in the field of neurodegenerative diseases, and to work in a dynamic and collaborative environment. We offer a competitive salary package, including an estimated annual salary of €60,000 - €80,000, depending on experience and qualifications.



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