VP Clinical Development

VP Clinical Development — Autoimmunity | Clinical-stage biotech, Remote Looking for a VP Clinical Development to lead the clinical strategy and design of an autoimmunity / immunology programme moving through early and mid-stage development. Rheumatology, UC and Auto-immunity has seen a huge new wave of interest and investment. The coming together of technologies such as CART, Immuno-Oncology and increased life expectancies has seen new investment, approaches and trials. My client is currently one such company
- recent pharma investment, multiple clinical trials and now testing their platform in Autoimmune diseases. So, if you are passionate about auto-immunity clinical trial design and want to help a biotech who are growing into a new area -please keep reading About the opportunity A well-funded, clinical-stage biotech with a differentiated immuno-modulatory approach in autoimmune / inflammatory disease. Strong science, clean data to date, and a lean team where senior people have real influence over direction. This is a build role at an inflection point, not a maintenance one. Role responsibilities
* Own clinical development strategy for the autoimmunity programme: indication selection, development pathway, and the design of the trials that de-risk it.
* Lead protocol design, endpoint strategy, and the scientific rationale underpinning study concepts through to full protocols.
* Translate emerging clinical and translational data into decisions on future development plans and portfolio direction.
* Provide the medical and scientific lead on trial execution, including oversight of study conduct, data interpretation, and safety.
* Contribute to and review key regulatory and clinical documentation (development plans, briefing documents, IND/IMPD-type submissions, investigator brochures).
* Partner across translational research, regulatory, medical affairs, and operations to keep clinical strategy aligned and moving.
* Build and manage a small team, with a plan to add one to two hires (permanent or consulting) as the data and strategy dictate. Requirements
* MD required
- or Ph.
D if previous work was in Immunology or Autoimmunity.
* Clinical development experience (any indication
- Immunology / autoimmunity is a plus). The only exception are people who are \"purists\"
- so if you have only worked for example in oncology and nothing else, could be tricky. Apply anyway, but want to be upfront with you.
* Track record designing Phase I–III trials (Ideally II / POC studies).
* Comfortable operating hands-on in a lean biotech: strategic when needed, in the detail when needed.
* Based in the EU, able to travel to the German HQ around 4–5 days per month (a 1 week block is fine)
- (relocation to Germany welcome but not required). Right vs Wrong
* This is perfect for
- people who are Senior Director / VP already. They want flexibility in their work and like the idea of helping a company enter the next stages of growth. Unafraid to drive projects themselves and enjoy working with smaller teams / get sh-t done mentality.
* Not right for
- people looking for a CMO role. People with no trial design / clinical development it will not work (i.e. Medical Affairs, Safety etc). I need end to end trial design experience. People who want to lead 10 programs or direct reports (that is big pharma, not biotech).
* Could be right for
- maybe open to very experienced consultants who are willing to work 3-4 days a week. You will need strong Auto-immune / Immunology for this. The offer
* €150,000 – €210,000 base salary, depending on experience + 15% Bonus.
* Hybrid: home based within the EU, with ~4–5 days per month at the German HQ (a major German city).
* A genuine leadership seat: you shape the programme and the team, working directly with the executives
- reporting into C Suite. (CEO, CMO, CSO)
* Join at a pivotal, data-rich moment with room to grow the role as the pipeline advances.
* Small, supportive, science-driven team. An environment that's genuinely supportive of young families. As always, a human (me, Charles) wrote this, and a human will read every application. I can't promise personalised feedback, but I'll do my best to give everyone at least a clear yes or no. So if you want to own the clinical strategy of a differentiated autoimmunity programme at a biotech that's small enough for it to matter
- I'd love to hear from you. #J-18808-Ljbffr