Research Biostatistician
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Location:
Remote We are engaging Biostatisticians to contribute their clinical statistics expertise to a dynamic customer project focused on AI-assisted clinical research. In this role, you'll apply your expertise to help train next-generation AI systems. Your work will shape how models learn, reason, and perform through high-quality, real-world input. No prior experience in AI is required — your domain knowledge is what matters. Scope of Work
* Author and review evaluation tasks that require deriving, reproducing, or validating statistical outputs from clinical datasets and associated tables, figures, and listings (TFLs).
* Apply expert judgment to assess the correctness and consistency of reported estimates, confidence intervals, p-values, analysis populations, and missing data handling in alignment with the statistical analysis plan (SAP).
* Identify discrepancies between statistical outputs and their narrative descriptions in clinical study reports (CSR), including subtle errors in population definitions, censoring rules, or multiplicity handling.
* Establish defensible ground truth for each evaluation task, documenting the derivation process to enable independent verification.
* Provide structured written rationales distinguishing true statistical errors from acceptable methodological alternatives, employing clear and concise communication.
* Collaborate with a multidisciplinary project team, providing statistical insights and feedback as needed to refine evaluation tasks and criteria. Preferred Qualifications
* 5+ years as a biostatistician supporting clinical trials at a sponsor, CRO, or academic trials unit.
* Hands-on experience producing or quality controlling TFLs for regulatory submissions and working directly from CDISC SDTM/ADaM datasets.
* Solid understanding of statistical methods used in confirmatory trials, including survival analysis, mixed models, covariate adjustment, multiplicity control, and estimand and missing-data strategies under ICH E9(R1).
* Proficiency in SAS and/or R, with the ability to independently reproduce analyses from written specifications.
* Ability to interpret SAPs and ensure reported results are consistent with pre-specified analyses.
* Advanced degree (MSc or PhD) in Biostatistics, Statistics, or a closely related quantitative field.
* Nice to have: Experience as lead statistician on pivotal/registrational studies, authoring or reviewing CSR statistical sections, oncology endpoint expertise, and exposure to AI-assisted statistical review tools.
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