PhD offer within the Immune Therapies group, CIMA Universidad de Navarra, for the 26/27 Academic Year

hace 1 semana

Pamplona, Navarra, España Cima Universidad de Navarra A tiempo completo

The Immune Therapies Group, led by Dr. Juan Roberto Rodríguez is looking for a candidate to carry out the doctoral thesis for the 26/27 academic year.

Adoptive cell therapy
against cancer
is a type of immunotherapy that is based on
the use of agents that enhance the immune cells of the patients to stimulate specific antitumor responses
. The use of
genetically modified T cells
, and in particular
chimeric antigen receptor T (CAR-T) cells
, is one of
the most innovative and promising advanced therapies for the treatment of cancer
.

CAR-T therapies have demonstrated
high antitumoral efficacy in certain B-cell hematological malignancies
, such as
acute lymphoblastic leukemia (ALL)
,
non-Hodgkin lymphoma (NHL)
or
Multiple Myeloma (MM)
. However, in some cases like MM, there is a lack of long-term response, and in other malignant conditions, such as acute myeloid leukemia or solid tumors, the efficacy of these treatments needs to be demonstrated.

The Immune Therapies group, integrated in the
Cancer Center Clínica Universidad de Navarra
, comprises
a multidisciplinary team of basic and clinical researchers
focused on: i) the development and characterization of innovative CAR-T therapies in advanced preclinical models; ii) the implementation of CAR-T therapies for clinical use; iii) the characterization of the molecular mechanisms involved in the responses and resistance to these treatments.

Our group belongs the "
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC)
" and the "
Red de Terapias Avanzadas (TERAV)
" of the
Carlos III Health Institute
(ISCIII), as well as to several national and
international research and academic centers
.

Last Publications

Requirements
The Immune Therapies Group, led by Dr. Juan Roberto Rodríguez, is seeking for a creative, ambitious and highly motivated candidate to joint as a PhD student. The candidate will join a highly collaborative environment with the opportunity to apply cutting-edge genomic technologies on the field of Hematology Oncology. The work will be in permanent collaboration with an interactive international team of basic and translational researchers and in collaboration with the Computational Biology Program at CIMA.

The candidate must have a University degree in Sciences (Biology, Biochemistry, Pharmacy, Biotechnology…) with at least 8/10 marks (For those studies outside of Spain, we would need the equivalent marks through ). Moreover, the candidate must be currently enrolled in a Master's program that grants access to doctoral studies, with a planned completion date of September/October 2026, or already completed in 2025.

Knowledge on Computational Biology / Bioinformatics will be valued

Mandatory, attach CV, motivational letter and University degree marks / equivalent marks

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