PhD offer within the In vivo Organ Generation by Stem Cells group, CIMA Universidad de Navarra, for the 26/27 Academic Year
hace 2 semanas
The In vivo Organ Generation by Stem Cells Group, led by Dr. Xabier Aranguren is looking for a candidate to carry out the doctoral thesis for the 26/27 academic year.
Organ transplantation
is a very effective life-saving treatment for end-stage organ diseases. Nevertheless,
the number of organs available for transplantations is limited
, and the waiting lists are ever increasing, recently counting around people Europe and in USA, leading to a high rate of death for organ failure: only in the European continent, approximately 5.000 people die every year waiting for an organ, with a mortality rates for patients waiting for a heart, liver or lung ranging between 15 and 30%.
The necessity to find additional source of organs for transplantation has boosted research on the generation of organs from pluripotent stem cells (PSCs)
.
We develop new therapeutic alternatives based on the generation of xeno-organs in vivo by blastocyst complementation using pluripotent stem cells. This strategy is based on the microinjection of stem cells into genetically modified embryos, incapable of generating a certain type of organ/cell type. In this way the target organ is formed exclusively from the microinjected stem cells. The group works with mouse and rat embryonic stem cells and human iPS cells, as well as with genetically modified mouse and pig models.
Last Publications
Requirements
The In vivo Organ Generation by Stem Cells Group, led by Dr. Xabier Aranguren, is seeking for a creative, ambitious and highly motivated candidate to joint as a PhD student. The candidate will join a highly collaborative environment with the opportunity to apply cutting-edge genomic technologies on the field of Biomedical Engineering. The work will be in permanent collaboration with an interactive international team of basic and translational.
The candidate must have a University degree in Sciences (Biology, Biochemistry, Pharmacy, Biotechnology…) with at least 8/10 marks (For those studies outside of Spain, we would need the equivalent marks through ). Moreover, the candidate must be currently enrolled in a Master's program that grants access to doctoral studies, with a planned completion date of September/October 2026, or already completed in 2025.
Knowledge on Computational Biology / Bioinformatics will be valued
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