Neural Regeneration Specialist in Biomataterials Research
hace 1 semana
Company Overview
Somma is a leading research institution dedicated to advancing the field of biomaterials and neural regeneration. Our multidisciplinary team is passionate about developing innovative solutions for spinal cord injuries and diseases.
About the Role
We are seeking a highly motivated PhD candidate to join our Biomaterials for Neural Regeneration research group in Barcelona. This fully funded position offers a unique opportunity to work on an exciting project focused on developing advanced extracellular matrix (ECM) platforms for iPSC-derived spinal cord organoids.
Project Overview
The successful candidate will design, develop, and characterize novel ECM platforms, including hydrogel-based matrices with bioactive sequences and structured scaffolds. These platforms will be used to enhance the growth, maturation, and functionality of spinal cord organoids and motor neurons derived from iPSCs. The project aims to address current limitations in iPSC-based models of the spinal cord by tailoring ECM biomaterials to specific stages of spinal cord development and disease modeling.
Main Responsibilities
The PhD candidate will be responsible for:
- Design and Development: Create novel ECM platforms, including hydrogel-based matrices with bioactive sequences and structured scaffolds, to mimic the physiological conditions of the spinal cord environment at various developmental stages.
- Characterization and Optimization: Perform a comprehensive biochemical, structural, and functional analysis of the developed ECM platforms using state-of-the-art techniques such as mass spectrometry-based proteomics, single-cell RNA sequencing, and electrophysiological assessments.
- Application in Disease Modeling: Utilize the optimized ECM platforms to advance the fidelity of iPSC-derived spinal cord models for studying neurodevelopmental and neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA).
Requirements
We are looking for a highly motivated PhD candidate who is eager to engage in interdisciplinary research in the fields of biomaterials, tissue engineering, and neuroscience. The ideal candidate would meet the following criteria:
- Educational Background: A Master's degree in Biomedical Engineering, Neuroscience, Tissue Engineering, or a closely related field is preferred.
- Laboratory Experience and Technical Skills: Experience working in a wet lab setting is highly recommended. Familiarity with biomaterials, stem cell culture, or 3D biofabrication techniques would be advantageous.
- Teamwork and Communication: We value candidates who enjoy working collaboratively in a multidisciplinary team, have strong problem-solving skills, and can effectively communicate their research findings through both oral and written presentations.
Salary and Benefits
This PhD position comes with a competitive salary of approximately €35,000 per year, commensurate with experience. Additionally, Somma offers a range of benefits, including health insurance, retirement plan, and paid vacation time.
How to Apply
If you are a driven and enthusiastic researcher looking to make a meaningful contribution to the field of biomaterials and neural regeneration, please submit your application, including your CV, research statement, and contact information for three academic referees.
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