PhD Student – Single Cell Genomics of Blood Stem Cell Clones

hace 1 mes

Barcelona, Barcelona, España Centre for Genomic Regulation (CRG) A tiempo completo
About the Role

The Centre for Genomic Regulation (CRG) is seeking a highly motivated PhD student to join our Single Cell and Synthetic Genomics of Blood Formation lab. As a PhD student, you will be part of an interdisciplinary team investigating the biology of hematopoietic stem cells using single cell genomics, genetic screens, and computational biology.

Our lab focuses on developing novel genomic and bioinformatic tools to answer longstanding questions in the field. We are particularly interested in understanding the clonal dynamics of blood formation in ageing and hematological disease. The successful candidate will have the opportunity to work on a cutting-edge project, developing and applying single cell DNA methylome methods to investigate clonal function in ageing and disease.

Key Responsibilities
  • Develop and lead a project on clonal dynamics of blood formation in ageing and hematological disease
  • Analyze data from single cell DNA methylome methods
  • Interact with other bioinformaticians in the group to advance the EPI-Clone method and related methods for clonal tracking
  • Collaborate with wetlab and computational scientists from the group
About the Team

Our lab is a dynamic and interdisciplinary team of researchers, technicians, and clinicians working together to advance our understanding of hematopoietic stem cells. We strive to create a stimulating environment that fosters collaboration, innovation, and professional growth. As a PhD student, you will have the opportunity to work with experienced researchers and clinicians, and to contribute to the development of novel genomic and bioinformatic tools.

Requirements
  • M.Sc. degree in a relevant field (computational biology, genomics, biomedicine, bioinformatics)
  • Strong interest in single cell genomics technology and stem cell biology
  • Research experience in computational biology (at least 6 months of research work on a single project)
  • Excellent grades in quantitative disciplines (mathematics, physics, etc.) throughout studies
  • Strong programming skills in R or Python
What We Offer
  • 4-year contract
  • Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.
  • Target start date: January 2025

We offer a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. We promote a diverse and inclusive environment and welcome applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

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