Post Doc In The Mechanics Of Organelle Remodeling And Cell And Tissue Dynamics Laboratory
hace 1 mes
.Post Doc in the Mechanics of Organelle Remodeling and Cell and Tissue Dynamics LaboratoryThe InstituteThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed of an interdisciplinary, motivated, and creative scientific team supported by a flexible and efficient administration and high-end, innovative technologies.The successful candidate will address a critical question in mechanobiology: how mechanical forces relate to nuclear RNA-processing organelles (biomolecular condensates) in health and/or disease? Using interdisciplinary approaches, the candidates will explore how cytoskeletal forces impact nuclear dynamics across scales, from organelle remodeling down to RNA-processing regulation, and how this physical link influences cell division.About the team/lab/departmentA prominent research focus of the Al Jord Lab is the relation between physical forces and the remodeling of essential nuclear RNA-processing organelles known as biomolecular condensates. We pioneered in revealing that, in germ cells, cytoskeletal forces mechanically remodel and regulate nuclear condensates across scales for reproductive success. Whether somatic cells, which compose the majority of cells in an organism, evolved this mechanical mechanism of organelle remodeling remains a mystery. However, our new evidence indicates that this mechanism is deployed by mammalian somatic cells within diverse physiological and pathological contexts. We aim to venture into these unexplored grounds of nuclear condensate mechano-regulation across somatic cell types in health and disease. The research objective is to decipher how cytoskeletal forces impact nuclear dynamics across scales, from organelle remodeling down to RNA-processing regulation, and how this physical link influences somatic cell division and specialization. Our research follows a cross-disciplinary approach, bridging methods from systems, cell, molecular, and synthetic biology along with computational and biophysical tools, including techniques like protein multiplexing, advanced imaging, optogenetics, and force measurement and modulation assays.Whom would we like to hire?Professional experienceMust HaveThe candidate must hold a PhD, preferably in Cell & Molecular Biology, Oncology, or Biophysics.Lab experience with mammalian cell culture and common techniques in Cell & Molecular biology.Experience with advanced imaging and image analyses.Desirable but not required/Nice to have1. Experience with transcriptomics.LanguagesFluency in English.Advanced MS Office and Prism experience.Skilled with image and data analyses software.CompetencesRigor, organization, and autonomy.Strong analytical, interpersonal, and communication skills.Curiosity and critical thinking
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Barcelona, España Centre For Genomic Regulation A tiempo completo.Post Doc in the Mechanics of Organelle Remodeling and Cell and Tissue Dynamics LaboratoryThe InstituteThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed of an interdisciplinary, motivated, and creative...
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Barcelona, España Centre de Regulació Genòmica (CRG) A tiempo completoCentre de Regulació Genòmica (CRG). 1 plaça de Post Doc in the Mechanics of Organelle Remodeling and Cell and Tissue Dynamics Laboratory. Concurs o valoració de mèrits. Laboral temporal. 2024-10-04. Termini obert. A1 - Grau universitari (correspondència amb llicenciatures). Doctorat, preferiblement en biologia cel-lular i molecular, oncologia o...
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Barcelona, España Centre For Genomic Regulation A tiempo completoPost Doc in the Mechanics of Organelle Remodeling and Cell and Tissue Dynamics Laboratory The Institute The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries.The CRG is composed of an interdisciplinary, motivated, and creative...
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Barcelona, España Centre For Genomic Regulation A tiempo completoPost Doc in the Mechanics of Organelle Remodeling and Cell and Tissue Dynamics LaboratoryThe Institute The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed of an interdisciplinary, motivated, and creative...
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Barcelona, España Centre For Genomic Regulation A tiempo completoPost Doc in the Mechanics of Organelle Remodeling and Cell and Tissue Dynamics LaboratoryThe InstituteThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed of an interdisciplinary, motivated, and creative...
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Barcelona, España Center For Genomic Regulation A tiempo completo.The InstituteThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed of an interdisciplinary, motivated and creative scientific team supported by a flexible and efficient administration and by high-end and...
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Barcelona, España Center For Genomic Regulation A tiempo completoThe Institute The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries.The CRG is composed of an interdisciplinary, motivated and creative scientific team supported by a flexible and efficient administration and by high-end and...
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Barcelona, España Center For Genomic Regulation A tiempo completoThe InstituteThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed of an interdisciplinary, motivated and creative scientific team supported by a flexible and efficient administration and by high-end and...
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Barcelona, España Center for Genomic Regulation A tiempo completo**The Institute** The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by...
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Barcelona, Barcelona, España Center For Genomic Regulation A tiempo completoAbout the RoleThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with over 400 scientists from 44 countries. We are seeking a highly motivated and talented researcher to join our team and contribute to our cutting-edge research in mechanobiology.Research FocusThe successful...
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Barcelona, Barcelona, España Center For Genomic Regulation A tiempo completoAbout the RoleThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with over 400 scientists from 44 countries. We are seeking a highly motivated and talented researcher to join our team and contribute to our cutting-edge research in mechanobiology.Research FocusThe successful...
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Barcelona, Barcelona, España Centre For Genomic Regulation A tiempo completoAbout the Centre for Genomic RegulationThe Centre for Genomic Regulation (CRG) is a leading international biomedical research institute based in Barcelona, Spain. Our team of over 400 scientists from 44 countries is dedicated to advancing our understanding of the molecular mechanisms underlying life.Job DescriptionWe are seeking a highly motivated...
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Barcelona, Barcelona, España Centre For Genomic Regulation A tiempo completoAbout the Centre for Genomic RegulationThe Centre for Genomic Regulation (CRG) is a leading international biomedical research institute based in Barcelona, Spain. Our team of over 400 scientists from 44 countries is dedicated to advancing our understanding of the molecular mechanisms underlying life.Job DescriptionWe are seeking a highly motivated...
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Barcelona, Barcelona, España Centre For Genomic Regulation A tiempo completoAbout the Centre for Genomic RegulationThe Centre for Genomic Regulation (CRG) is a leading international biomedical research institute based in Barcelona, Spain. Our team of over 400 scientists from 44 countries is dedicated to advancing our understanding of the molecular mechanisms underlying life.Job DescriptionWe are seeking a highly motivated...
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Barcelona, Barcelona, España Centre For Genomic Regulation A tiempo completoAbout the Centre for Genomic RegulationThe Centre for Genomic Regulation (CRG) is a leading international biomedical research institute based in Barcelona, Spain. Our team of over 400 scientists from 44 countries is dedicated to advancing our understanding of the molecular mechanisms underlying life.Job DescriptionWe are seeking a highly motivated...
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Postdoc Position in The ‘cell and Tissue
hace 4 meses
Barcelona, España Center for Genomic Regulation A tiempo completo**The Institute** The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by...
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Barcelona, Barcelona, España Barcelona Institute Of Science And Technology (Bist) A tiempo completoThe RoleWe are seeking a highly motivated and skilled Stem Cell and Gene Editing Specialist to join our Tissue Engineering Unit. The successful candidate will provide patient-derived organoid (PDO) and mouse and human pluripotent 2D and 3D stem cell differentiation procedures, as well as CRISPR/Cas9 gene editing services.The ideal candidate will be able to...
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Group Leader
hace 3 días
Barcelona, España European Molecular Biology Laboratory A tiempo completo.Science FacultyBarcelona, SpainEMBL Barcelona is a research unit focusing on Tissue Biology and Disease Modelling. We build tissues to understand them, either in vitro or in silico. We go beyond the molecular and cellular scale to ask questions such as: How do thousands of cells dynamically self-organise to create tissues and organs? How do new emergent...
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Barcelona, Barcelona, España Barcelona Institute Of Science And Technology (Bist) A tiempo completoJob DescriptionThe Centre for Genomic Regulation (CRG) is a leading international biomedical research institute based in Barcelona, Spain. We are seeking a highly motivated and experienced Stem Cell and Gene Editing Specialist to join our Tissue Engineering Unit.The successful candidate will provide patient-derived organoid (PDO) and mouse and human...
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Quantitative Cell Biology Researcher
hace 4 días
Barcelona, Barcelona, España Barcelona Institute Of Science And Technology (Bist) A tiempo completoThe Centre for Genomic Regulation (CRG) is a core-funded interdisciplinary institute with strengths encompassing genomics, systems, computational, cell and molecular biology.We are currently looking for a Junior Group Leader in Quantitative Cell Biology to join our team.The successful applicant will use multidisciplinary approaches to address fundamental...
