Research Scientist For The Digital Genomics Group
hace 1 mes
Descripción We are looking for an enthusiastic and accomplished Research Scientist to join the Digital Genomics lab, focusing on cutting-edge cancer genomics research.
This is a unique opportunity to develop next-generation cancer biomarkers by leveraging mutational signatures, germline predisposition variants, and other cancer genomics features.
We aim to advance our understanding of how diverse genetic and environmental factors shape tumor development and how this knowledge can be translated into clinical settings to provide a better prognostic stratification and treatment selection for cancer patients.
In the newly formed Digital Genomics lab (PI: Marcos Díaz-Gay), we are in the pursuit of understanding better the mechanisms behind the accumulation of genomic alterations in human tumors to benefit cancer diagnosis, prognosis, and treatment selection.
By analyzing mutational patterns in tumors, we can identify the mutational processes active during the tumorigenesis process.
Thus, specific patterns of mutations, known as mutational signatures, are generated by different environmental (e.g., ultraviolet light exposure), lifestyle (e.g., tobacco smoking), and endogenous processes (e.g., defective DNA repair mechanisms).
Mutational signatures can be extracted from next-generation sequencing (NGS) data using machine learning artificial intelligence (AI) approaches and assigned to individual tumors for patient-level analyses, as previously shown (Islam & Díaz-Gay et al.
2022 Cell Genomics, Senkin et al.
2024 Nature).
We invite applications from senior postdoctoral researchers with a strong background in cancer genomics/epigenomics/transcriptomics, human genetics, or related fields, who are eager to shape the future of personalized cancer care.
As the lab is in its founding stage, this position offers the chance to make a foundational impact and help shape a collaborative and dynamic team, fostering a supportive and inclusive work environment.
Key responsibilities: • Develop next-generation AI-driven cancer biomarkers based on different genomics alterations and apply them to routine clinical sequencing data.
• Analyze diverse genomic data to assess population- and sex-specific differences in mutational processes, incorporating germline factors that influence cancer predisposition and progression.
• Collaborate closely with national and international partners to refine and validate biomarkers for clinical application.
"La financiación de estos contratos, procede del Mecanismo de Recuperación y Resiliencia de la Unión Europea-Next Generation, en el marco de la Invitación General de la entidad pública empresarial Red.es para participar en los programas de atracción y retención del talento dentro de la Inversión 4 del Componente 19 del Plan de Recuperación, Transformación y Resiliencia."Criterios de evaluaciónEssential experience and skills: • PhD in biomedicine, computational biology, bioinformatics, machine learning, artificial intelligence, or related disciplines.
• At least 4 years of experience after PhD.
• Experience in cancer genomics/epigenomics/transcriptomics or human genetics.
• Track record of publications and conference communications in the field.
• Proficiency in at least one programming language (preferably R and/or Python).
• Solid level of spoken and written English.
Desirable experience and skills: • Background knowledge in one of the following: colorectal or lung cancer biology, DNA repair, somatic mutagenesis, or machine learning methods for omics data.
• Experienced with molecular biology techniques (wet lab).
• Experienced with high-performance computing (HPC) cluster systems and/or cloud computing.
• Hands-on experience with bioinformatics tools for one of the following analyses: mutational signatures, mutation calling, or tumor evolution.Se ofrece• The opportunity to be part of an internationally renowned cancer research center of excellence.
• Collaborative, supportive, and inclusive work environment.
• Competitive salary.
• Contract linked to a project.
-
Research Scientist For The Digital Genomics Group
hace 3 semanas
Madrid, España Cnio A tiempo completo.DescripciónWe are looking for an enthusiastic and accomplished Research Scientist to join the Digital Genomics lab, focusing on cutting-edge cancer genomics research.This is a unique opportunity to develop next-generation cancer biomarkers by leveraging mutational signatures, germline predisposition variants, and other cancer genomics features.We aim to...
-
Research Scientist For The Digital Genomics Group
hace 3 semanas
Madrid, España Cnio A tiempo completoDescripción We are looking for an enthusiastic and accomplished Research Scientist to join the Digital Genomics lab, focusing on cutting-edge cancer genomics research.This is a unique opportunity to develop next-generation cancer biomarkers by leveraging mutational signatures, germline predisposition variants, and other cancer genomics features.We aim to...
-
Research Scientist For The Digital Genomics Group
hace 3 semanas
Madrid, España Cnio A tiempo completoDescripciónWe are looking for an enthusiastic and accomplished Research Scientist to join the Digital Genomics lab, focusing on cutting-edge cancer genomics research.This is a unique opportunity to develop next-generation cancer biomarkers by leveraging mutational signatures, germline predisposition variants, and other cancer genomics features.We aim to...
-
Research Scientist for the Digital Genomics Group
hace 2 semanas
Madrid, España CNIO A tiempo completoDescripciónWe are looking for an enthusiastic and accomplished Research Scientist to join the Digital Genomics lab, focusing on cutting-edge cancer genomics research.This is a unique opportunity to develop next-generation cancer biomarkers by leveraging mutational signatures, germline predisposition variants, and other cancer genomics features.We aim to...
-
Madrid, España CNIO A tiempo completoDescripción We are looking for an enthusiastic and accomplished Research Scientist to join the Digital Genomics lab, focusing on cutting-edge cancer genomics research. This is a unique opportunity to develop next-generation cancer biomarkers by leveraging mutational signatures, germline predisposition variants, and other cancer genomics features. We aim to...
-
Research Scientist for the Digital Genomics Group
hace 22 horas
Madrid, España CNIO A tiempo completoDescripción We are looking for an enthusiastic and accomplished Research Scientist to join the Digital Genomics lab, focusing on cutting-edge cancer genomics research. This is a unique opportunity to develop next-generation cancer biomarkers by leveraging mutational signatures, germline predisposition variants, and other cancer genomics features. We aim to...
-
Research Scientist for the Digital Genomics Group
hace 1 semana
Madrid, España CNIO A tiempo completoDescripciónWe are looking for an enthusiastic and accomplished Research Scientist to join the Digital Genomics lab, focusing on cutting-edge cancer genomics research.This is a unique opportunity to develop next-generation cancer biomarkers by leveraging mutational signatures, germline predisposition variants, and other cancer genomics features.We aim to...
-
Cancer Genomics Research Scientist for Innovative Solutions
hace 3 semanas
Madrid, Madrid, España Cnio A tiempo completoWe are seeking an accomplished Research Scientist to join the Digital Genomics lab at Cnio. As part of our team, you will focus on cutting-edge cancer genomics research and develop next-generation cancer biomarkers using mutational signatures, germline predisposition variants, and other cancer genomics features.Our goal is to advance our understanding of how...
-
Madrid, Madrid, España CNIO A tiempo completoWe are seeking a highly motivated Research Scientist to join our Digital Genomics Group at CNIO, a world-renowned cancer research center of excellence. Our team is dedicated to understanding the mechanisms behind the accumulation of genomic alterations in human tumors, with the ultimate goal of improving cancer diagnosis, prognosis, and treatment...
-
Madrid, España Cnio A tiempo completoDescripción We are looking for a highly motivated postdoc to join the Digital Genomics lab, focusing on cutting-edge cancer genomics research.This is a unique opportunity to develop next-generation cancer biomarkers by leveraging mutational signatures, germline predisposition variants, and other cancer genomics features.We aim to advance our understanding...
-
Madrid, España Cnio A tiempo completo.DescripciónWe are looking for a highly motivated postdoc to develop innovative computational methods to analyze mutational signatures and tumor evolution using human cancer sequencing data.In the newly formed Digital Genomics lab (PI: Marcos Díaz-Gay), we aim to better understand the mechanisms behind the accumulation of genomic alterations in human...
-
Madrid, España Cnio A tiempo completoDescripción We are looking for a highly motivated postdoc to develop innovative computational methods to analyze mutational signatures and tumor evolution using human cancer sequencing data.In the newly formed Digital Genomics lab (PI: Marcos Díaz-Gay), we aim to better understand the mechanisms behind the accumulation of genomic alterations in human...
-
Madrid, España Cnio A tiempo completoDescripciónWe are looking for a highly motivated postdoc to develop innovative computational methods to analyze mutational signatures and tumor evolution using human cancer sequencing data.In the newly formed Digital Genomics lab (PI: Marcos Díaz-Gay), we aim to better understand the mechanisms behind the accumulation of genomic alterations in human tumors...
-
Madrid, España CNIO A tiempo completoDescripción We are looking for a highly motivated postdoc to develop innovative computational methods to analyze mutational signatures and tumor evolution using human cancer sequencing data. In the newly formed Digital Genomics lab (PI: Marcos Díaz-Gay), we are in the pursuit of understanding better the mechanisms behind the accumulation of genomic...
-
Madrid, España Cnio A tiempo completoDescripción We are looking for a highly motivated postdoc to develop innovative computational methods to analyze mutational signatures and tumor evolution using human cancer sequencing data.In the newly formed Digital Genomics lab (PI: Marcos Díaz-Gay), we are in the pursuit of understanding better the mechanisms behind the accumulation of genomic...
-
Senior Research Scientist For Advanced Genomic Analysis
hace 3 semanas
Madrid, Madrid, España Cnio A tiempo completoCnio is a leading organization in the field of digital genomics, and we are currently seeking an experienced Senior Research Scientist to join our team. The successful candidate will be responsible for developing innovative computational methods to analyze mutational signatures and tumor evolution using human cancer sequencing data.
-
Epidemiologist For Malaria Physiopathology
hace 2 semanas
Madrid, España Isglobal A tiempo completo.Organisation/Company: ISGLOBALDepartment: HR DEPARTMENTResearch Field: Medical sciences, Biological sciences, Computer scienceResearcher Profile: First Stage Researcher (R1)Country: SpainApplication Deadline: 31 Dec 2024 - 17:00 (Europe/Madrid)Type of Contract: TemporaryJob Status: Full-timeIs the job funded through the EU Research Framework Programme? Not...
-
Principal Research Assistant in Applied Microbial Genomics
hace 4 semanas
Madrid, Madrid, España ICTAN-CSIC A tiempo completoJob Title: Laboratory Technician in Molecular MicrobiologyAre you interested in a challenging and rewarding career in molecular microbiology? We are seeking a highly motivated and skilled Laboratory Technician to join our team at the Applied Microbial Genomics Unit.The ideal candidate will have a strong background in molecular biology, genetics, or a related...
-
Madrid, Madrid, España Cnio A tiempo completoCareer Opportunities at CNIOThe Structural Biology programme at the Spanish National Cancer Research Centre (CNIO) is seeking a highly skilled and motivated bioinformatician to join our team.**Job Summary:**We are looking for an experienced specialist in bioinformatics with expertise in high-throughput sequencing data analysis, computational tool...
-
Madrid, España Cnio A tiempo completoDescripciónWe are looking for a Senior Scientist to join Roger Castells-Graells' lab at the Spanish National Cancer Research Centre (CNIO).This position involves leading innovative projects in biochemistry, protein design, structural biology, and virology, as part of the newly established Biomolecular Design and Structural Nanomedicine lab.Our research...
