Research Scientist For The Digital Genomics Group
hace 6 días
Descripción We are looking for an enthusiastic and accomplished Research Scientist to join the Digital Genomics lab, focusing on cutting-edge cancer genomics research.
This is a unique opportunity to develop next-generation cancer biomarkers by leveraging mutational signatures, germline predisposition variants, and other cancer genomics features.
We aim to advance our understanding of how diverse genetic and environmental factors shape tumor development and how this knowledge can be translated into clinical settings to provide a better prognostic stratification and treatment selection for cancer patients.
In the newly formed Digital Genomics lab (PI: Marcos Díaz-Gay), we are in the pursuit of understanding better the mechanisms behind the accumulation of genomic alterations in human tumors to benefit cancer diagnosis, prognosis, and treatment selection.
By analyzing mutational patterns in tumors, we can identify the mutational processes active during the tumorigenesis process.
Thus, specific patterns of mutations, known as mutational signatures, are generated by different environmental (e.g., ultraviolet light exposure), lifestyle (e.g., tobacco smoking), and endogenous processes (e.g., defective DNA repair mechanisms).
Mutational signatures can be extracted from next-generation sequencing (NGS) data using machine learning artificial intelligence (AI) approaches and assigned to individual tumors for patient-level analyses, as previously shown (Islam & Díaz-Gay et al.
2022 Cell Genomics, Senkin et al.
2024 Nature).
We invite applications from senior postdoctoral researchers with a strong background in cancer genomics/epigenomics/transcriptomics, human genetics, or related fields, who are eager to shape the future of personalized cancer care.
As the lab is in its founding stage, this position offers the chance to make a foundational impact and help shape a collaborative and dynamic team, fostering a supportive and inclusive work environment.
Key responsibilities: • Develop next-generation AI-driven cancer biomarkers based on different genomics alterations and apply them to routine clinical sequencing data.
• Analyze diverse genomic data to assess population- and sex-specific differences in mutational processes, incorporating germline factors that influence cancer predisposition and progression.
• Collaborate closely with national and international partners to refine and validate biomarkers for clinical application.
"La financiación de estos contratos, procede del Mecanismo de Recuperación y Resiliencia de la Unión Europea-Next Generation, en el marco de la Invitación General de la entidad pública empresarial Red.es para participar en los programas de atracción y retención del talento dentro de la Inversión 4 del Componente 19 del Plan de Recuperación, Transformación y Resiliencia."Criterios de evaluaciónEssential experience and skills: • PhD in biomedicine, computational biology, bioinformatics, machine learning, artificial intelligence, or related disciplines.
• At least 4 years of experience after PhD.
• Experience in cancer genomics/epigenomics/transcriptomics or human genetics.
• Track record of publications and conference communications in the field.
• Proficiency in at least one programming language (preferably R and/or Python).
• Solid level of spoken and written English.
Desirable experience and skills: • Background knowledge in one of the following: colorectal or lung cancer biology, DNA repair, somatic mutagenesis, or machine learning methods for omics data.
• Experienced with molecular biology techniques (wet lab).
• Experienced with high-performance computing (HPC) cluster systems and/or cloud computing.
• Hands-on experience with bioinformatics tools for one of the following analyses: mutational signatures, mutation calling, or tumor evolution.Se ofrece• The opportunity to be part of an internationally renowned cancer research center of excellence.
• Collaborative, supportive, and inclusive work environment.
• Competitive salary.
• Contract linked to a project.
-
Madrid, España CNIO A tiempo completoDescripción We are looking for an enthusiastic and accomplished Research Scientist to join the Digital Genomics lab, focusing on cutting-edge cancer genomics research. This is a unique opportunity to develop next-generation cancer biomarkers by leveraging mutational signatures, germline predisposition variants, and other cancer genomics features. We aim to...
-
Madrid, España CNIO A tiempo completoDescripción We are looking for a highly motivated postdoc to develop innovative computational methods to analyze mutational signatures and tumor evolution using human cancer sequencing data. In the newly formed Digital Genomics lab (PI: Marcos Díaz-Gay), we are in the pursuit of understanding better the mechanisms behind the accumulation of genomic...
-
Madrid, España Cnio A tiempo completoDescripción We are looking for a highly motivated postdoc to develop innovative computational methods to analyze mutational signatures and tumor evolution using human cancer sequencing data.In the newly formed Digital Genomics lab (PI: Marcos Díaz-Gay), we are in the pursuit of understanding better the mechanisms behind the accumulation of genomic...
-
Madrid, España CNIO - Spanish National Cancer Research Centre A tiempo completo```htmlDescripciónThe Spanish National Cancer Research Centre (CNIO) is one of the top leading cancer research institutes in Europe, hosting world-renowned scientists that have made significant contributions in both basic and translational aspects of cancer biology.The Transformation and Metastasis laboratory led by Dr. Gonzalez Suarez is funded by several...
-
Research Scientist
hace 4 semanas
Madrid, Madrid, España CEU Educational Group A tiempo completoResearch Scientist PositionWe are seeking a highly motivated Research Scientist to join our team at CEU San Pablo University. The successful candidate will be part of a dynamic research group focused on understanding the molecular determinants underlying the immunopathologic immune response associated with Influenza virus and respiratory bacteria...
-
Research Scientist
hace 4 semanas
Madrid, Madrid, España CEU Educational Group A tiempo completoResearch Scientist PositionWe are seeking a highly motivated Research Scientist to join our team at CEU San Pablo University. The successful candidate will be part of a dynamic research group focused on understanding the molecular determinants underlying the immunopathologic immune response associated with Influenza virus and respiratory bacteria...
-
Research Assistant for Genomics and Bioinformatics
hace 3 semanas
Madrid, Madrid, España CNIO - Spanish National Cancer Research Centre A tiempo completo**Job Opportunity at CNIO**We are seeking a highly motivated Predoctoral Research Assistant to join our team at the CNIO - Spanish National Cancer Research Centre.The successful candidate will have a strong background in bioinformatics and genomics, with experience in processing and analyzing large-scale data sets. Proficiency in Python and Unix/Linux...
-
Madrid, Madrid, España ICTAN-CSIC A tiempo completoJob Title: Laboratory Technician in Molecular MicrobiologyAre you interested in a challenging and rewarding career in molecular microbiology? We are seeking a highly motivated and skilled Laboratory Technician to join our team at the Applied Microbial Genomics Unit.The ideal candidate will have a strong background in molecular biology, genetics, or a related...
-
Research Scientist for Cancer Biology
hace 4 semanas
Madrid, Madrid, España CNIO - Spanish National Cancer Research Centre A tiempo completoAbout the PositionWe are seeking a highly motivated postdoctoral/research scientist to join our team at the Spanish National Cancer Research Centre (CNIO). The successful candidate will have a PhD in a relevant discipline and at least three years of experience as a postdoctoral scientist.Key ResponsibilitiesConduct research in cancer biology and immunity,...
-
Research Scientist for Cancer Biology
hace 4 semanas
Madrid, Madrid, España CNIO - Spanish National Cancer Research Centre A tiempo completoAbout the PositionWe are seeking a highly motivated postdoctoral/research scientist to join our team at the Spanish National Cancer Research Centre (CNIO). The successful candidate will have a PhD in a relevant discipline and at least three years of experience as a postdoctoral scientist.Key ResponsibilitiesConduct research in cancer biology and immunity,...
-
Research Scientist
hace 3 semanas
Madrid, Madrid, España Sitio web oficial A tiempo completoResearch Scientist OpportunityWe are seeking a highly motivated and talented Research Scientist to join our team at the FUNDACION INSTITUTO INVESTIGACION SANITARIA FUNDACION JIMENEZ DIAZ. As a Research Scientist, you will have the opportunity to work on a Predoctoral Contract for Training in Health Research (PFIS) project, focusing on Cellular and Molecular...
-
Research Scientist
hace 3 semanas
Madrid, Madrid, España Sitio web oficial A tiempo completoResearch Scientist OpportunityWe are seeking a highly motivated and talented Research Scientist to join our team at the FUNDACION INSTITUTO INVESTIGACION SANITARIA FUNDACION JIMENEZ DIAZ. As a Research Scientist, you will have the opportunity to work on a Predoctoral Contract for Training in Health Research (PFIS) project, focusing on Cellular and Molecular...
-
Research Scientist in Polymers
hace 4 semanas
Madrid, Madrid, España EHU A tiempo completoResearch Scientist in PolymersThe Polymer and Soft Matter Group at the Center of Materials Physics at EHU is seeking a highly motivated Research Scientist to join our team. The successful candidate will have a strong background in polymer synthesis and experimental methods such as calorimetric and spectroscopy techniques.Key Responsibilities:Conduct research...
-
Research Scientist in Polymers
hace 4 semanas
Madrid, Madrid, España EHU A tiempo completoResearch Scientist in PolymersThe Polymer and Soft Matter Group at the Center of Materials Physics at EHU is seeking a highly motivated Research Scientist to join our team. The successful candidate will have a strong background in polymer synthesis and experimental methods such as calorimetric and spectroscopy techniques.Key Responsibilities:Conduct research...
-
Madrid, Madrid, España CNIO A tiempo completoJob Opportunity at CNIOThe Computational Oncology Group at the Spanish National Cancer Centre (CNIO) is seeking a highly skilled postdoctoral researcher to contribute to the development of computational approaches for cancer research. As a member of our team, you will work closely with lab members and clinical collaborators to advance our understanding of...
-
Madrid, Madrid, España CNIO A tiempo completoJob Opportunity at CNIOThe Computational Oncology Group at the Spanish National Cancer Centre (CNIO) is seeking a highly skilled postdoctoral researcher to contribute to the development of computational approaches for cancer research. As a member of our team, you will work closely with lab members and clinical collaborators to advance our understanding of...
-
Madrid, Madrid, España Cnio A tiempo completoJob Opportunity: The Computational Oncology Group at the Spanish National Cancer Centre (CNIO) is seeking a highly skilled postdoctoral researcher to contribute to the development of computational approaches for guiding chemoprevention of cancer.About The Role:As a postdoctoral researcher in our group, you will work closely with lab members and clinical...
-
Research Scientist
hace 3 semanas
Madrid, Madrid, España Sitio web oficial A tiempo completoResearch Scientist OpportunityWe are seeking a highly motivated and talented Research Scientist to join our team at the FUNDACION INSTITUTO INVESTIGACION SANITARIA FUNDACION JIMENEZ DIAZ. The successful candidate will have the opportunity to work on a Predoctoral Contract for Training in Health Research (PFIS) project, focusing on Cellular and Molecular...
-
Research Scientist
hace 3 semanas
Madrid, Madrid, España Sitio web oficial A tiempo completoResearch Scientist OpportunityWe are seeking a highly motivated and talented Research Scientist to join our team at the FUNDACION INSTITUTO INVESTIGACION SANITARIA FUNDACION JIMENEZ DIAZ. The successful candidate will have the opportunity to work on a Predoctoral Contract for Training in Health Research (PFIS) project, focusing on Cellular and Molecular...
-
Madrid, Madrid, España CNIO A tiempo completoAbout the RoleWe are seeking a highly skilled Postdoctoral Research Assistant to join our Computational Oncology Group at the Spanish National Cancer Centre (CNIO). The successful candidate will work closely with our team to develop computational approaches to help guide the chemoprevention of cancer.Key ResponsibilitiesDevelop and apply computational...
