Postdoctoral Researcher At The At The Pluripotency For Organ Regeneration Research Group

Institute for bioengineering of Catalonia, IBEC

Organisation/Company Institute for bioengineering of Catalonia, IBEC Research Field Biological sciences Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Application Deadline 30 Nov ***:59 (Europe/Madrid) Country Spain Type of Contract Temporary Job Status Full-time Hours Per Week 37.5 Is the job funded through the EU Research Framework Programme? Other EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Introduction to the vacant position:

The Pluripotency for organ regeneration Group at the Institute for Bioengineering of Catalonia (IBEC) is looking for a Junior Post-doctoral Researcher up to 3 years after PhD thesis defense, to conduct her/his postdoctoral training on the development of advanced human organoid platforms based on hPSC for disease modelling and drug screening applications.

Main tasks and responsibilities:

- Application of engineering approaches to define controlled cell-to-cell and cell-to-ECM microenvironments to enhance organoid differentiation and reproducibility, including synthesis of biomimetic hydrogels, development of organ-on-chip approaches and 3D bioprinting.
- Development of scalable human organoid differentiation approaches from human pluripotent stem cells (hPSCs) in 2D and 3D cell culture settings.
- Development and implementation of quantitative and qualitative assays to monitor molecular and metabolic changes, and cell/tissue functionality during organoid development in 2D and 3D cell culture settings.
- Definition of standardized operational procedures (SOPs).
- Data Analysis & Scientific Output: Independently analyse complex datasets, prepare high-impact scientific publications, and present research findings at international conferences.
- Mentorship & Project Management: Supervise and mentor PhD and Master's students within the research group, while overseeing project milestones and preparing technical reports, as assigned by the PI.

Requirements for candidates:

- PhD in the field of biology, biotechnology, biomedical engineering, biomedicine or similar areas
- Only candidates who are within 3 years of their PhD thesis defense, are eligible to this position.
- Proved knowledge on culture and differentiation of human pluripotent stem cells (hPSC) (specifically on methodologies to derive hPSC-organoids will be a plus), confocal microscopy and quantitative image analysis, as well as molecular biology techniques.
- Proved experience in bioengineering technologies (i.e. microfabrication, biomaterials, organ-on-chip, bioprinting approaches).

- Ability to work independently and manage complex projects under tight deadlines, experience mentoring junior researchers (MSc or PhD students), excellent scientific writing and presentation skills, teamwork, proactivity, and critical/analytical thinking.
- Competencies and skills: Communication, Teamwork and collaboration, Commitment, Proactivity, Integrity, Critical and Analytical thinking.
- High level of English

Advantageous:

- Application of quantitative imaging approaches in 2D and 3D organoid settings and live imaging setups. Experience in developing custom made scripts for image processing and quantification.
- Experience in analysis of RNA sequencing data (bulk and single cell RNA seq).

We Offer:

- Number of available positions: 1
- Starting date: January **
- Working conditions:
- Full- timeOpen-ended contract due to technical and scientific activities linked to the project and budget duration.
- Measures to reconcile work and family life (parental leave, versátil schedule working hours, 23 working days of paid holidays, 9 leave days for personal matters, among others).
- IBEC ensures equality of access to professional development opportunities irrespective of employment status, length at IBEC or other factors. The IBEC's yearly training catalogue offers a wide range of training in technical and transferable skills including mobility grants and a Mentoring programme for predoctoral and postdoctoral researchers.
- Stimulating, interdisciplinary research and high-quality international scientific environment.
- Induction programme to facilitate incorporation at IBEC and additional support is provided for foreigners to obtain Visa-working permit and to install in Barcelona.

Only those applications submitted before the deadline will be evaluated.

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