Postdoctoral Fellow
hace 7 días
Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.
The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people's quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science.
Its 28 laboratories and seven core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer's, diabetes, and rare conditions.
IRB Barcelona is an international centre that hosts 400 members and 30 nationalities. It is located in the Barcelona Science Park.IRB Barcelona forms part of the Barcelona Institute of Science and Technology (BIST) and the "Xarxa de Centres de Recerca de Catalunya" (CERCA).
Large-scale small molecule bioactivity data are not routinely integrated in daily biological research to the extent of other 'omics' information. Compound data are scattered and diverse, making them inaccessible to most researchers and not suited to standard statistical analyses. We recently developed the Chemical Checker (CC), a resource that provides processed, harmonized and integrated bioactivity data on small molecules (Duran-Frigola et al. 2020 Nat Biotechnol; Bertoni et al. 2021 Nat Commun). We showed how CC signatures can boost the performance of drug discovery tasks that typically capitalize on chemical descriptors, and we demonstrated and experimentally validated that CC signatures can be used to reverse and mimic biological signatures of disease models and genetic perturbations, options that are otherwise impossible using chemical information alone. We are now developing a generalized connectivity mapping, as a form of virtual phenotypic screening, to discover novel chemical or genetic modulators able to revert the specific signatures of disease and 'cancel out' the phenotypic traits of complex disorders. In particular, we aim at developing new chemical entities able to specifically target pancreatic cancer cell lines, without affecting other similar cells.
This contract will be part of the project I+D+i PID RB-I00, financed by MCIN/AEI/ /
DUTIES:
EXPERIENCE, KNOWLEDGE, SKILLS:
Must Have - Required
-
Education: Bachelor in Biosciences. PhD in Pharmacology, Molecular or Cell biology.
-
Experience: previous experience in working with complex diseases, including molecular and cellular models. Strong publications record according to his/her career stage.
-
Skills:
- Experience with standard biochemistry, molecular and cell biology techniques.
- Experience in CRISPR-Cas9, RNAi, target validation and drug screening.
- Knowledge of 'omics technologies and highthroughout approaches.
- Positive organizational, problem solving and communication skills.
Desirable
-
Experience: Previous experience working on cancer cell lines and animal models.
WORKING CONDITIONS & ENTITLEMENTS:
-
Working conditions: Permanent contract. Employed in compliance with Spanish legislation and regulations under a full-time contract. Employees receive the benefits of the Spanish Social Security system covering sickness, maternity/paternity leaves and injuries at work.
-
Training and Career:Postdoctoral researchers joining IRB Barcelona gain access to the Institute's advanced research training and career development opportunities, all within in a competitive international environment. Courses and workshops on themes of particular interest to postdocs are offered regularly by the Institute.
-
Estimated annual gross salary: Salary commensurate with experience and qualifications.
-
International environment:Nearly 90 Postdoctoral researchers (more than a half non
- Spanish nationals) are currently working at IRB Barcelona.
HOW TO APPLY & SELECTION PROCESS:
Number of positions available: 1
Selection process:
-
Pre-selection: Will be based on CV, motivation letter & experience.
-
Plaça de Postdoctoral Fellow Cido
hace 7 días
Barcelona, Barcelona, España Institut de Recerca Biomèdica (IRB) A tiempo completoInstitut de Recerca Biomèdica (IRB). 1 plaça de Postdoctoral Fellow. Concurs o valoració de mèrits. Laboral temporal Termini obert. A1 - Grau universitari (correspondència amb llicenciatures). Doctorat en Química, Física, Ciències de la Computació, Bioinformàtica, Biotecnologia, Biomedicina o similar. Anglès fluïtVeure convocatòria- Contracte...
-
Places de Postdoctoral Research Fellow in
hace 1 semana
Barcelona, Barcelona, España Universitat de Barcelona (UB) A tiempo completoUniversitat de Barcelona (UB). 2 places de Postdoctoral Research Fellow in Philosophy - TAMP. Concurs o valoració de mèrits. Laboral temporal Termini obert. A1 - Grau universitari (correspondència amb llicenciatures). Títol de doctorat en FilosofiaVeure convocatòria- Contracte laboral indiferent- Jornada indiferent
-
Plaça de Postdoctoral Fellow at The Epigenetic
hace 1 semana
Barcelona, Barcelona, España Centre de Regulació Genòmica (CRG) A tiempo completoCentre de Regulació Genòmica (CRG). 1 plaça de Postdoctoral fellow at the epigenetic face of cancer metabolism. Concurs o valoració de mèrits. Laboral temporal Termini obert. A1 - Grau universitari (correspondència amb llicenciatures). Doctor en Biomedicina o afins. Nívell expert d'anglèsVeure convocatòria- Contracte laboral indiferent- Jornada...
-
Postdoctoral Fellow
hace 7 días
Barcelona, Barcelona, España Somm Excellence Alliance A tiempo completoIRB Barcelona seeks a talented Postdoctoral Fellow to join our structural bioinformatics team in the Molecular Modeling and Bioinformatics group (Structural Bioinformatics Program), under the framework of the "XNA-Hub" initiative, funded by the Instituto de Salud Carlos III witihin the project PMPTA23/00006.DUTIES:EXPERIENCE, KNOWLEDGE, SKILLS:Must Have -...
-
Postdoctoral Research Fellow
hace 7 días
Barcelona, Barcelona, España RMIT VN A tiempo completoOverview: Postdoctoral Research Fellow to deliver on RMIT Europe's objectives under the ALCOAT Project funded by the EU Research Fund for Coal & Steel (RFCS) Based in Barcelona, collaborative and dynamic international team High level proficiency in English and working rights in Spain Flexible work environment including remote working Full time, continuing...
-
Postdoctoral Fellow
hace 1 semana
Barcelona, Barcelona, España IRB Barcelona A tiempo completoCreated in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people's quality of...
-
Postdoctoral Fellow for The Cellular Plasticity
hace 1 semana
Barcelona, Barcelona, España IRB Barcelona A tiempo completoCreated in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people's quality of...
-
Barcelona, Barcelona, España IRB Barcelona A tiempo completoCreated in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people's quality of...
-
Postdoctoral Fellow in Pathogenic Yeast Genomics
hace 1 semana
Barcelona, Barcelona, España IRB Barcelona A tiempo completoCreated in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people's quality of...
-
Postdoctoral Fellow
hace 1 semana
Barcelona, Barcelona, España Center for Genomic Regulation A tiempo completoThe InstituteThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end...
-
Postdoctoral Fellow On Biological Data Sciences
hace 7 días
Barcelona, Barcelona, España Somm Excellence Alliance A tiempo completoViral infections, together with human genetics, constitute major risk factors for developing complex diseases. However, the molecular and physiological mechanisms of how these viral infections cause and contribute to non-communicable disease development are unknown thus hampering prevention and therapeutic approaches. CLARITY will take advantage of...
-
Postdoctoral Fellow On Biological Data Sciences
hace 7 días
Barcelona, Barcelona, España IRB Barcelona A tiempo completoCreated in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people's quality of...
-
Barcelona, Barcelona, España Irb Barcelona A tiempo completoCreated in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people's quality of...
-
Barcelona, Barcelona, España IRB Barcelona A tiempo completoCreated in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people's quality of...
-
Barcelona, Barcelona, España IRB Barcelona A tiempo completoCreated in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people's quality of...
-
Barcelona, Barcelona, España Somma A tiempo completoIRB Barcelona is seeking two experimental Postdoctoral Researchers in pathogenic yeast genomics and evolution to join the Comparative Genomics group, led by ICREA professor Toni Gabaldón.The Comparative Genomics group ), which is jointly affiliated to the Barcelona Supercomputing Centre (BSC-CNS), is involved in multiple projects covering a wide range of...
-
Post-doctoral Position in Neuromonitoring of
hace 7 días
Barcelona, Barcelona, España Somm Excellence Alliance A tiempo completoICFO is offering a postdoctoral position to a well-qualified, highly motivated and dynamic young scientist who wishes to enhance his/her scientific career in a friendly and stimulating environment.ICFO Medical Optics group led by ICREA professor Turgut Durduran is a partner in Horizon Europe project "Preterm Brain-Oxygenation and Metabolic EU-Sensing: Feed...
-
Barcelona, Barcelona, España ICN2 A tiempo completoThe mission of the Catalan Institute of Nanoscience and Nanotechnology (ICN2) is to achieve the highest level of scientific and technological excellence in Nanoscience and Nanotechnology. Its research lines focus on the newly-discovered physical and chemical properties that arise from the behaviour of matter at the nanoscale. ICN2 has been awarded with the...
-
Barcelona, Barcelona, España Icn2 A tiempo completoThe mission of the Catalan Institute of Nanoscience and Nanotechnology (ICN2) is to achieve the highest level of scientific and technological excellence in Nanoscience and Nanotechnology. Its research lines focus on the newly-discovered physical and chemical properties that arise from the behaviour of matter at the nanoscale. ICN2 has been awarded with the...
-
Postdoctoral Fellow On Biological Data Sciences
hace 1 semana
Barcelona, Barcelona, España Somm Excellence Alliance A tiempo completoViral infections, together with human genetics, constitute major risk factors for developing complex diseases. However, the molecular and physiological mechanisms of how these viral infections cause and contribute to non-communicable disease development are unknown thus hampering prevention and therapeutic approaches. CLARITY will take advantage of...
