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Research technician in the Intracellular Compartmentation lab
hace 2 semanas
The Institute
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research' logo from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).
Please, check out our Recruitment Policy
The role
The Malhotra lab is looking to hire a research technician. The candidate will work together with scientists in the lab on ongoing projects, focussing mainly on Golgi apparatus organization and function, and the process of secretion of bulky cargoes such as collagens, mucins and chylomicrons. They will work with the Group Leader on a specific project related to the mechanism by which GRASP family of proteins function in unconventional secretion and with a postdoc, specifically, to develop procedures for testing the function of TANGO1 and its binding partner in skin fibrosis.
About the lab
The Intracellular compartmentation lab studies different aspects of protein secretion. Protein secretion is an old problem of fundamental interest in cell biology. While over the last decades a lot of progress has been made in understanding protein secretion, a number of questions remain unsolved. The lab aims to understand different aspects of this. On the one hand they study the process whereby cytoplasmic, signal sequence lacking proteins are secreted from cells upon certain stimuli (known as unconventional protein secretion). On the other hand they focus on the transport and secretion of large, complex cargoes (like collagens and mucins) that do not fit the conventional secretory pathway.
Whom would we like to hire?
Professional experience
Must Have
You have experience in cell biology and biochemistry
You have proven experience with molecular biology, tissue culture work, microscopy imaging
You have proven experience in gene editing technologies (e.g. Cripsr-Cas9 editing of tissue culture cell lines)
Education and training
- You hold a MSc in disciplines such as biochemistry, biology, biomedical sciences
Languages
- You are proficient in English
Technical skills
You have cellular, molecular biology and microbiological skills
You have experience in gene editing techniques in tissue culture cells
You have knowledge of DNA & RNA techniques
You have imaging skills (epifluorescence as well as confocal microscopy, fixed cells as well as life cell imaging)
You have experience in protein analysis techniques
You have advanced software skills (MS Office, Adobe Acrobat, ImageJ)
Competences
Excellent organisational skills
Works well in a team, but is also capable of working in an independent manner
Attention to detail
The Offer – Working Conditions
Contract duration: Technical and scientific activities contract linked to the project duration (estimated until 31/8/2027).
Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.
Target start date: As soon as possible.
We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.
We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, race, religion or sexual orientation.
The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.
