Postdoctoral Research Scientist

hace 2 semanas

Santiago de Compostela, La Coruña, España Servizo Galego de Saúde A tiempo completo

Overview
The tumor microenvironment lab, part of ONCOMET () , at the Health Research Institute of Santiago de Compostela (IDIS), is looking for a postdoctoral researcher to join our team.

Our group studies new therapeutic strategies in high grade gliomas based on biophysical strategies, with a particular focus on the immune and non-immune tumor microenvironment.

We are located at the University Clinical Hospital of Santiago de Compostela, and we have a daily and fluent connection with the Medical Oncology, Neurosurgery, Radiotherapy and Neuroimaging clinical departments, which makes our research highly translational.

About The Project
The GlioProof project, funded in the **** private-public collaboration call (AEI), will be developed in close collaboration with Batea Oncology () , a startup developing therapeutic solutions for Glioblastoma patients, as well as with 3 leading hospitals in Spain.

The project has a strong clinical orientation, as it aims at bringing a biomaterial-based therapeutic strategy to a Phase I clinical trial in Glioblastoma patients.

As well, we will perform fundamental/translational research in order to deepen into the mechanisms of action of such biomaterials, as well as in exploring new potential therapeutic combinations.

Your tasks

Perform 2D/3D in vitro assays with biomaterials, and cellular models, including primary glioma organoids.

Developing new potential models.

Monitor cell behaviour applying flow citometry, advanced microscopy, RNASeq and proteomic based techniques, among others.

Perform in vivo experiments, including orthotopic glioma models (mice and rats, immunocompetent and immunodeficient), or others.

Study the combined effects of biomaterial implants with radiation/chemotherapy or immunotherapies.

Analyse patient-derived samples (tissue and blood) from patients recruited in the Phase I trial.

Actively collaborate with other projects in the lab, as well as with national and international partners.

What are we looking for?

PhD

in cancer biology, biotechnology, bioengineering or related field.

Experience with cell culture, primary cell culture/organoids will be an asset.

Demonstrated experience with animal models.

Having an active animal experimentation license is a must.

Fast learning and able to conduct experiments independently.

Good writing data plotting skills.

Presentation skills will be valued.

Strong organizational skills, working confortably in a fast-paced environment.

Easy-going, collaborative, enthusiastic, proactive person, able to work in multidisciplinary environments.

Fluent in English, Spanish is an asset but not required.

What do we offer?

You will be part of a youg, dynamic and supportive lab environment.

The possibility to work on a genuinely translational project, and take an active part on the development of a phase I clinical trial, in collaboration with a startup

2 year working contract

, competitive salary based on experience.

Expected starting date: January ****

How to apply

Send to ******:

CV with experience and publications

Motivation letter

2 references with contact information

Applications not including all this information will not be taken into consideration

Deadline to apply: November 15th ****

J-*****-Ljbffr

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