Global Clinical Program Lead, Hematology

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. We are more than one of the world’s leading pharmaceutical companies.

AstraZeneca has a multifaceted environment that cultivates collaboration and innovation. We attract top minds, and we nurture and build talent.

Within Hematology R&D, we are committed to advancing the science to deliver life-changing medicines to patients most in need. With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death. This unit has responsibility for the value chain from discovery through to late-stage development, enabling rapid acceleration of promising early-stage assets and life-cycle management programs.
- Accountable for the delivery of project according to quality, time, budgets and resources
- Build strategic and coordinated clinical development plans which are aligned with business objectives and are differentiated from competitor products.
- Accountable for the execution of the integrated product plan to agreed scope, timelines, and budgets
- Leads and communicates the clinical development strategy at governance meetings, accountable for aligning with internal management and for communicating with external collaborators.
- Lead clinical aspects of projects from preclinical Lead Optimization Investment Decision to clinical Proof of Concept (PoC):

- Responsible for all clinical aspects of project strategy including translational, clinical development, patient selection, regulatory, pediatric, and Asian development strategy
- Development of the Target Product Profile, ensuring alignment with disease area strategy and late stage development
- Co-leads the Clinical ProgramTeam (CPT) to effectively run/mitigate/communicate risk, make decisions, and handle conflict and change.
- Responsible for maintaining a high degree of CPT effectiveness through collaboration, influence, and, as necessary, coaching and mentoring of cross-functional team members.
- Ensure that there are robust processes, plans and data to enable Governance Bodies to make investment decisions and prioritize projects across the portfolio.

**Minimum Qualifications**:

- M.D. is required
- A minimum of 7 years of relevant experience
- Industry experience in drug development including experience in early and late phase drug development and regulatory knowledge.
- Strong knowledge and understanding of the Hematology Oncology therapeutic area with experience in diverse biological mechanisms.
- Broad understanding of the evolving clinical landscape in hematology/oncology
- Lead the overall development of project strategy and be accountable for project plans, timelines, progress, and outcomes.
- Proven experience mentoring and motivating teams in a highly matrixed environment.
- Proven record of encouraging and leading internal and external cross-functional collaborations
- Demonstrated organizational and project management skills
- Proven success in influencing colleagues and senior leaders in various departments.
- Must demonstrate high integrity.

**Working at AstraZeneca**

Here you’ll have the chance to create a substantial difference to patients’ lives With science at its heart, this is the place where breakthroughs born in the lab become transformative medicines - for the world’s most complex diseases. Answer unmet medical needs by pioneering the next wave of science, focusing on outcomes and crafting the patient ecosystem.

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