Research Officer for The Mass Spectrometry

Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.

The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people’s quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science. Its 29 laboratories and seven core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer’s, diabetes, and rare conditions.

IRB Barcelona is an international centre that hosts 500 members and 45 nationalities. It is located in the Barcelona Science Park. IRB Barcelona forms part of the Barcelona Institute of Science and Technology (BIST) and the “Xarxa de Centres de Recerca de Catalunya” (CERCA).

IRB Barcelona seeks to recruit a dedicated **Research Officer** to join our **Mass Spectrometry & Proteomics Core Facility**. We are a highly experienced team committed to excellence in proteomics, equipped with cutting-edge instrumentation and methodologies. Our mission is to provide comprehensive support to uncover the role of proteins across diverse biological systems. We deliver professional, customised proteomics services at the forefront of biomedical and translational research, serving both the IRB scientific community and external public and private partners.

Do you have hands-on experience in proteomics workflows? Are you eager to learn the latest proteomics strategies? Would you like to join an integrative team passionate about mass spectrometry and proteomics? **Then this opportunity is for you**.

As a Research Officer, you will perform MS-based proteomics experiments, contributing to all stages of the proteomics workflow and supporting high-impact research projects.

**Key responsabilities**
- Experimental preparation of samples: cell and tissue lysis, protein extraction, digestion and quantification, TMT labelling, phospho-enrichment of proteins, sample fractionation, and depletion of abundant proteins in plasma and cerebrospinal fluid, among other techniques.
- Data acquisition using next-generation mass spectrometers
- Data analysis using dedicated proteomics software such as Proteome Discoverer, Spectronaut, DIA-NN, among others.
- Execution and support of spatial proteomics analyses using dedicated protocols and new-generation instrumentation.
- Calibration and maintenance of equipment including mass spectrometers, liquid chromatographs, and sample preparation robots.
- Help preparation of detailed results reports for users.
- Providing assistance and guidance to users.

**You have**
- **Knowledge**: A degree in chemistry, biochemistry, pharmacy, biology or related fields.
- **Experience**:

- In proteomics, both in experimental workflows and data analysis pipelines.
- In data acquisition in orbitraps and high resolution mass spectrometers. Experience in the use of specialized proteomics software (MaxQuant, Sequest, MassLynx, Proteome Discoverer, PEAKS, Spectronaut).
- Operation of sample preparation robots, including BeatBox, Opentrons platform.
- **Skills**:In clinical samples proteomic analysis. Knowledge of laboratory techniques and safety protocols.
- Experience in supervision of interns and trainees.
- Strong organizational and multitasking skills.
- Attention to detail and accuracy.
- Highly motivated and collaborative person. Good teamworker.
- Willing to keep on learning.

**You might also have**
- A Master’s Degree in biomedical, Health sciences or related fields.
- **Knowledge**: In modern proteomic strategies: interactomics, immunopeptidomics, spatial and single cell proteomics.
- **Skills**: Organized and dynamic person, with initiative and highly motivated to work in a research environment within a Core Facility. Willing to work for users projects. Good communication skills and fluency in English.

**What we offer**:
**To be a part a part of something meaningful**: We are a biomedical research centre that tirelessly works to achieve a society free of diseases. Our mission is to carry out research of excellence to cure cancer and other diseases linked to ageing.

**Good Working conditions**: Employed in compliance with Spanish legislation and regulations under a full-time contract. Employees receive the benefits of the Spanish Social Security system covering sickness, maternity/paternity leave and injuries at work.

**Competitive salary**: commensurate with experience and qualifications.

**International Environment**: we are home to nearly 500 researchers, technical and support staff from 45 countries.

**To be a member of our State-of-the-Art Core Facilities**:Scientists at IRB Barcelona thrive with unparalleled support from our extensive Core Facilities, equipped with the latest technologies and scientific services. These essential resou