•PhD offer within the Myelodysplastic Neoplasia group, CIMA Universidad de Navarra, for the 26/27 Academic Year
hace 2 días
The Myelodysplastic Neoplasia Group, led by Dr. Irene Gañán is looking for a candidate to carry out the doctoral thesis for the 26/27 academic year. Myelodysplastic syndromes (MDS) are genetically heterogeneous hematologic malignancies associated with aging and with the risk of developing acute myeloid leukemia. MDS arise with the expansion of hematopoietic stem cells with genetic and/or cytogenetic alterations in the bone marrow. Proliferation of aberrant cell clones induces ineffective differentiation, which in turn results in peripheral blood cytopenias. MDS patients have low survival rates due to their limited therapeutic options and the fact that these, for the most part, are not curative. Among the reasons for the historical lack of effective therapies against MDS are their great genetic heterogeneity and an incomplete understanding of the mechanisms that facilitate the survival and expansion of MDS stem cells. Our group, integrated in the Cancer Center Clínica Universidad de Navarra , investigates the cellular and molecular mechanisms that lead to the development of MDS, therapy failure and disease progression. To do so, we take a comprehensive approach , allowing us to put the mechanisms intrinsic to hematopoietic stem cells in context with the extrinsic mechanisms that enable their survival and expansion, using multidisciplinary methods and state-of-the-art techniques. Impact of our research Currently, the only curative therapy for MDS is bone marrow stem cell transplantation , for which only a small percentage of patients are candidates . Existing therapeutic alternatives for the remaining patients can correct the symptomatology in about half of them , but have a short-lasting effect and the appearance of resistance is associated with a very rapid progression of the disease. Characterization of the global spectrum of hematopoietic stem cell alterations and other cell lineages that lead to the onset, maintenance and progression of MDS will allow the identification of targets for the development of new therapies that can eliminate aberrant cells and prevent or slow disease progression . Last publications: The Myelodysplastic Neoplasia Group, led by Dr. Irene Gañán, is seeking for a creative, ambitious and highly motivated candidate to joint as a PhD student. The candidate will join a highly collaborative environment with the opportunity to apply cutting-edge genomic technologies on the field of Hematology Oncology. The work will be in permanent collaboration with an interactive international team of basic and translational researchers and in collaboration with the Computational Biology Program at CIMA. The candidate must have a University degree in Sciences (Biology, Biochemistry, Pharmacy, Biotechnology…) with at least 8/10 marks (For those studies outside of Spain, we would need the equivalent marks through ). Moreover, the candidate must be currently enrolled in a Master's program that grants access to doctoral studies, with a planned completion date of September/October 2026, or already completed in 2025. Knowledge on Computational Biology / Bioinformatics will be valued Include: CV, motivational letter and University degree marks / equivalent marks
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Pamplona, España Fundación para la Investigación Médica Aplicada A tiempo completoThe Immune Therapies Group, led by Dr. Juan Roberto Rodríguez is looking for a candidate to carry out the doctoral thesis for the 26/27 academic year. Adoptive cell therapy against cancer is a type of immunotherapy that is based on the use of agents that enhance the immune cells of the patients to stimulate specific antitumor responses . The use of...
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Pamplona, Navarra, España Cima Universidad de Navarra A tiempo completoThe In vivo Organ Generation by Stem Cells Group, led by Dr. Xabier Aranguren is looking for a candidate to carry out the doctoral thesis for the 26/27 academic year.Organ transplantationis a very effective life-saving treatment for end-stage organ diseases. Nevertheless,the number of organs available for transplantations is limited, and the waiting lists...
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Pamplona, España Fundación para la Investigación Médica Aplicada A tiempo completoThe Cardiac Tissue Engineering Group, led by Dr. Manuel Mazo is looking for a candidate to carry out the doctoral thesis for the 26/27 academic year. Cardiovascular diseases are the leading cause of death globally , and many of them lack effective treatment. The heart lacks sufficient capacity to repair itself after damage such as myocardial infarction . At...
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Pamplona, España Fundación para la Investigación Médica Aplicada A tiempo completoThe Immune Therapies Group, led by Dr. Juan Roberto Rodríguez is looking for a candidate to carry out the doctoral thesis for the 26 / 27 academic year.Adoptive cell therapy against cancer is a type of immunotherapy that is based on the use of agents that enhance the immune cells of the patients to stimulate specific antitumor responses . The use of...
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Pamplona, España Fundación para la Investigación Médica Aplicada A tiempo completoThe In vivo Organ Generation by Stem Cells Group, led by Dr. Xabier Aranguren is looking for a candidate to carry out the doctoral thesis for the 26/27 academic year. Organ transplantation is a very effective life-saving treatment for end-stage organ diseases. Nevertheless, the number of organs available for transplantations is limited , and the waiting...
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Pamplona, España Cima Universidad de Navarra A tiempo completoOrgan transplantation Organ transplantation is a very effective life-saving treatment for end-stage organ diseases. Nevertheless the number of organs available for transplantations is limited, and the waiting lists are ever increasing, recently counting around 150.000 people Europe and 100.00 in USA, leading to a high rate of death for organ failure. Only in...
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Pamplona, España Fundación para la Investigación Médica Aplicada A tiempo completoSe busca candidato para la realización de la tesis doctoral en el Curso 26/27 en el Grupo de Patología Mieloide del CIMA Universidad de Navarra. En las últimas décadas, el envejecimiento de la población ha llevado a un aumento en la incidencia de las enfermedades asociadas a la edad, incluyendo las neoplasias mieloides como los síndromes...
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Pamplona, España Universidad de Navarra A tiempo completoLa Universidad de Navarra, en su sede de Pamplona, **busca una persona para realizar una sustitución en el Servicio de Planificación y Mejora de la Docencia.** Las personas que pertenecen al Servicio se dedican: - Al asesoramiento y orientación de los procesos externos e internos de calidad de las facultades. - Están en contínuo contacto con los...
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Pamplona, España Universidad de Navarra A tiempo completoSe incorporará como Letrado de la Asesoría Jurídica de la Universidad de Navarra en Pamplona dentro de la Subdirección de Derecho Laboral y Seguridad Social. Contratación. Nuevas tecnologías. Dará asistencia técnica y asesoramiento letrado a los Servicios de Recursos Humanos de los distintos centros de la Universidad de Navarra en Pamplona, Madrid,...
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PhD Position: In Vivo Organ Generation from Stem Cells
hace 1 semana
Pamplona, España Cima Universidad de Navarra A tiempo completoA leading research institution in Spain is seeking a highly motivated candidate for a PhD position in the In vivo Organ Generation by Stem Cells Group. The candidate will collaborate in a dynamic environment, applying advanced genomic technologies in Biomedical Engineering. Required qualifications include a University degree in Sciences with a minimum of...
