Laboratory Research Assistant

hace 3 semanas


Badalona, Barcelona, España Institut Josep Carreras (Ijc) A tiempo completo

Your Mission

The Josep Carreras Leukaemia Research Institute (IJC) is a leading cancer research center dedicated to researching and driving innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukemia and other hematologic malignancies.

We are seeking a Laboratory Research Assistant to join our team and contribute to our mission of finding a cure for these diseases.

**Job Description:**

We are looking for an experienced Laboratory Research Assistant to support our team in the development of innovative immunotherapies for acute leukemia. The ideal candidate will have a strong background in laboratory techniques, including mouse handling, breeding, and welfare supervision.

Responsibilities:

  • Manage and breed immunodeficient mouse colonies, including NSG and NSGS strains.
  • Design and conduct in vivo experiments in close collaboration with researchers.
  • Supervise the development and evolution of experiments.
  • Administer substances by various routes, including intraperitoneal, intravenous, subcutaneous, intratibial, intrahepatic, oral gavage, etc.
  • Blood sampling from sub-mandibular and intracardiac sites.
  • Mouse biopsy and genotyping.
  • Mouse bone marrow aspirates.
  • In vivo imaging techniques, including bioluminescence.
  • Mouse euthanasia and tissue sampling.
  • Animal welfare supervision.

**Requirements:**

  • Accreditation according to R.D 53/2013 for animal care, euthanasia, procedure performance, project design, and on-site supervision.
  • Solid experience in mouse handling, breeding, and welfare supervision.
  • Experience with immunodeficient mice, patient-derived xenografts, and cancer models for disease initiation and treatment.
  • Ability to design experiments and discuss them openly with other researchers.
  • Molecular biology/biochemistry knowledge, haemocytometer, flow cytometry analysis skills, and cell culture knowledge are desirable.

**What We Offer:**

This contract is linked to the project PRYGN234975MENE, Next generation, off-the-shelf, CD1a/CCR9-directed dual CAR immunotherapy for relapse/refractory T-cell acute lymphoblastic leukemia.

The stimulating environment of the Barcelona metropolitan area.

Participation in innovative and multidisciplinary projects.

Opportunity for professional growth in an advanced research environment.

Working in the basic laboratory with strong collaborations with clinical researchers in the environment of the Josep Carreras Leukaemia Research Institute.

Estimated Salary: €35,000 - €45,000 per annum.



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