Synthetic Biotechnology Research Scientist

hace 3 semanas


Barcelona, Barcelona, España Centre For Genomic Regulation A tiempo completo

The Centre for Genomic Regulation (CRG) is a leading international biomedical research institute, based in Barcelona, Spain. Our interdisciplinary team of scientists from 44 countries work together to push the boundaries of synthetic biology and protein engineering.

About the Role

We are seeking an experienced Synthetic Biotechnology Research Scientist to lead the experimental testing and optimization of enzymes generated by our AI models. The successful candidate will be responsible for high-throughput screening and directed evolution approaches to manage and evaluate thousands of enzymes efficiently.

This role is crucial in experimentally validating the predictions made by our AI models, providing valuable feedback to improve the models over time. The candidate will have the opportunity to learn cutting-edge AI techniques and focus on the engineering of biotechnologically relevant enzymes.

About the Lab

You will join an interdisciplinary research group at the forefront of AI-driven protein design and engineering. Our team is highly collaborative, integrating computational scientists, experimental biologists, and biotechnologists to drive innovation in synthetic biology and protein engineering.

Key Responsibilities

  • Lead experimental testing and optimization of enzymes generated by our AI models
  • Develop high-throughput screening and directed evolution approaches to manage and evaluate thousands of enzymes efficiently
  • Collaborate with the research group to drive innovation in synthetic biology and protein engineering

Requirements

  • 3+ years of experience in protein engineering, specifically in the testing of enzyme variants
  • Wide experience in the implementation and screening of enzyme activity assays
  • Familiarity with directed evolution techniques and (ultra)-high throughput techniques

Desirable Qualifications

  • Experience with robotic liquid-handling platforms for high-throughput workflows and automation
  • Willingness to learn or constantly hear about machine learning methods for protein engineering and design

Educational Background

A PhD in Biochemistry, Chemistry, Molecular Biology, Biotechnology, or a related field is required. You should be proficient in English.

Technical Skills

  • Advanced skills in protein engineering techniques, such as mutagenesis, cell-free systems, and/or (ultra-) high-throughput assays
  • Ability to independently develop protocols to screen the activity, selectivity, and thermodynamics of enzyme variants
  • Experience automating systems for handling and screening thousands of protein variants

Salary and Benefits

The annual salary for this position is approximately €60,000 - €80,000, depending on experience. We also offer a comprehensive benefits package, including health insurance, retirement plan, and paid time off.

How to Apply



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