Computational Design Gene Editor
hace 1 semana
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed of an interdisciplinary, motivated and creative scientific team supported by a flexible and efficient administration and by high-end and innovative technologies.
Main Responsibilities
The candidate will train large language and diffusion models to provide new protein variants that will be tested in the laboratory. The main responsibilities will include implementing and using machine learning models for the design of gene writer sequences.
About the Team
This research group focuses on using computational and experimental approaches to understand and design protein functions. We have extensive experience in deep unsupervised learning and protein design, which we have applied to various projects. Over the next few years, we will expand our focus to include the design of custom-tailored and new-to-nature protein functions. We will implement models, understand their decision-making process using XAI, and improve their performance through reinforcement learning. We will also include experimental characterization efforts, allowing continual improvement of our models.
Requirements
We seek exceptional candidates with a passion for computation and deep learning to solve biomedical challenges. Experience in bioinformatics, computational structural biology, or computational biology is required. Good understanding of software engineering and good code practices is also necessary. The capability of working independently on very fast-paced science is essential. A PhD in Bioinformatics, Synthetic Biology or a related field is desirable but not required. Experience in protein or enzyme design, knowledge about gene editing technologies such as CRISPR-associated nuclease-based tools, and good communication skills in English are also desirable.
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Computational Design Gene Editor Specialist
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Madrid, Madrid, España Somma A tiempo completoAbout the RoleThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Spain, with over 400 scientists from 44 countries.We are seeking an exceptional candidate with a passion for computation and deep learning to join our AI for protein design group.The successful candidate will train large language...
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Madrid, Madrid, España Somma A tiempo completoAbout the RoleThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with over 400 scientists from 44 countries. We are seeking a talented Researcher to join our AI for protein design group, where you will work at the intersection of protein AI models and gene editing.Key...
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Madrid, Madrid, España Somma A tiempo completoAbout the RoleThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with over 400 scientists from 44 countries. We are seeking a talented Researcher to join our AI for protein design group, where you will work at the intersection of protein AI models and gene editing.Key...
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Madrid, Madrid, España Somma A tiempo completoAbout the RoleThe Centre for Genomic Regulation (CRG) is seeking a highly skilled Researcher to join our AI for protein design group. As a key member of our team, you will be responsible for implementing and using machine learning models for the design of gene writer sequences.About the TeamOur research group focuses on using computational and experimental...
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Researcher—Computational Design Gene Editors
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Madrid, Madrid, España Somma A tiempo completoAbout the RoleThe Centre for Genomic Regulation (CRG) is seeking a highly skilled Researcher to join our AI for protein design group. As a key member of our team, you will be responsible for implementing and using machine learning models for the design of gene writer sequences.About the TeamOur research group focuses on using computational and experimental...
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