Scientist - Computational Systems Biology
hace 5 meses
**Working with Us**
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
- CITRE, based in Seville, Spain, is Bristol Myers Squibb’s research institute in Europe, and our link to the European research community. _
- Informatics & Predictive Sciences at CITRE performs innovative computational research to inform decisions across all stages of drug development. Areas of research include computational and network biology, machine/deep learning, cheminformatics, predictive modeling, patient stratification, and method development for analysis and interpretation of biological data._
We seek an innovative **C**omputational Scientist** **with experience in Systems Biology** to join our team and contribute to the computational efforts at both early development and preclinical studies to guide translational research.
This position offers the opportunity to directly impact the origination and development of novel therapies in oncology with unmet medical needs, as well as broad exposure to diverse clinical and analytical research challenges.
**Responsibilities**
- Collaborate as a member of cross functional teams to design, analyze and interpret genomics, epigenetics and proteomics experiments for elucidating mechanisms of drug sensitivity/resistance and prioritizing synergistic combinations.
- Perform analysis of clinical and preclinical genomic datasets using integrative and ensemble learning approaches
- Participate in the scientific discussion of the results within a multidisciplinary team and translate the mechanistic findings from preclinical models to clinical settings
- Author scientific reports to publishable standard.
- Contribute to planning and execution of collaborative projects with leading academic and commercial research groups worldwide.
**Background experience & complementary knowledge**
- Ph.D. in computational biology, bioinformatics, biostatistics or related field from a recognized higher-education establishment.
- Statistical programming and data manipulation skills, using contemporary open-source bioinformatics tools (e.g., R/Bioconductor and Python) and databases using readable and reproducible code
- Experience in computational cancer research applied to oncology, hematology, immunoinflammatory and other therapeutic areas
- Demonstrated ability to infer molecular mechanisms from NGS data generated by perturbation of in-vitro, in-vivo and ex-vivo models using well stablished bioinformatics tools and statistical methods
- Familiarity with human interactome resources and databases (e.g., protein-protein interactions, regulatory and metabolic networks).
- Tracked record of peer-reviewed publications in top-tier scientific journals.
- Proven problem-solving skills, collaborative nature and adaptability across disciplines.
- Excellent verbal and written communication skills - fluent verbal and written English language skills prerequisite.
Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to gender identity, race, color, religion, sexual orientation, national origin or disability.
**Uniquely Interesting Work, Life-changing Careers**
**On-site Protocol**
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
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