Postdoc Position in The ‘cell and Tissue

hace 3 semanas

Barcelona, España Somm Excellence Alliance A tiempo completo

The Institute

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

The role

Cellular plasticity is a hallmark of metastasis and cancer aggressiveness. It involves morphodynamic cell changes and cell state transitions that act as drivers of cancer cell proliferation, dissemination and metastatic colonialization in different tissues and organs. The physical tissue environment is emerging as an important regulator of cell plasticity relevant to stem cell and cancer biology. We are offering a position in a European Project (PLAST_CELL) that aims to establish a novel quantitative standard to assess cell plasticity and to investigate molecular and biophysical mechanisms of plasticity in cancer stem cells.

About the lab

The Ruprecht lab combines methods from physics and biology to study fundamental mechanisms that control cell and tissue morphodynamics in development and disease. The group employs quantitative methods including advanced fluorescence microscopy, mechanobiology, synthetic biology and state-of-the-art cell and molecular biology techniques, Studies are performed both with animal model systems and bottom-up in vitro approaches to identify key mechanisms controlling mechano-chemical cell signalling, cell-cell interactions and multi-cellular selforganisation that establish the functional architecture of an organism. The research group is part of the Quantitative Cell Biology Program and Systems and Synthetic Biology Program at CRG.

Whom would we like to hire?

Professional experience

Must Have
- You have experience in the fields of cancer/stem cell biology
- You have expertise in the study of cellular morphodynamics and mechanobiology
- You have worked with in vitro cell culture methods
- You have experience in fluorescence microscopy and quantitative biology methods

Desirable but not required/ Nice to have
- You have experience in bioengineering and microfabrication and worked with 2D/3D cell and tissue culture methods
- You have experience with data processing and image analysis

Education and training
- You have a PhD degree in bioengineering, biochemistry, cell biology or a similar field

Languages
- You are fluent in English

Competences
- You are an independent thinker and creative problem-solver
- You are highly organized and responsible in your work tasks
- You have very good writing and communication skills
- You enjoy working in a team and an interdisciplinary research environment

The Offer - Working Conditions
- Contract duration: A minimum duration of 3 year with the option of extension
- Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales
- Target start date: As soon as possible

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

1. A motivation letter addressed to Dr Verena Ruprecht.

2. A complete CV including contact details.

3. Contact details of two referees.

Selection Process

Funded by the European Union with project number PLAST_CELL_101046620

**Deadline**: March 31, 2023
**Job category**: Postdoc
**Area**: Life Sciences

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