PhD Position in Neuroscience

27 Oct 2023
Job Information
Organisation/Company
Institute of Neurosciences
Research Field
Neurosciences » Neurophysiology
Neurosciences » Neurobiology
Researcher Profile
First Stage Researcher (R1)
Country
Spain
Application Deadline
24 Nov 2023 – 00:00 (Europe/Madrid)
Type of Contract
Temporary
Job Status
Full-time
Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

A PhD position is offered in the Neurophysiology Lab from Universitat de Barcelona and Institute of Neurosciences-UB. Within the research line of Synaptic Function in Chanelopathies leaded by Mercè Izquierdo-Serra ).

Cerebellar ataxia is a highly prevalent neurological disorder associated with several types of Congenital Disorders of Glycosylation (CDG)(1) The aim of the project is to study the impact of hypoglycosylation on the synaptic function of the cerebellum. Our hypothesis is that hypoglycosylation could lead to a Purkinje Cell dysfunction and consequently cause cerebellar ataxia.

To study the impact of synaptic function in cerebellar networks, we work with dissociated primary cerebellar cultures and cultured cerebellar mouse slices where glycosylation is globally disrupted to mimic the condition of CDG-patients. Then to assess synaptic function and synaptic protein localization we apply advanced techniques in neuroscience such electrophysiology (patch-clamp), optogenetics, calcium/voltage imaging or immunostaining techniques applied to cleared and normal tissue.

We seek a motivated PhD student who is interested in the field of neurophysiology and possesses experience in neuroscience techniques, critical thinking, independence and curiosity. The Neurophysiology Lab provides an excellent setting for pursuing a PhD. Throughout the doctoral program, we highly encourage participation in both national and international conferences, and international experience will be a priority. It is required an enthusiastic attitude, independent and team-work skills, willingness to learn as well as a good dedication to the lab work. Previous experience in a research lab will be well considered.

The successful candidate will receive salary funding for the first 12-18 months, with the expectation of securing additional fellowships to sustain their research thereafter.Therefore, a high academic score is required.

If you are interesed please send a short motivation/presentation letter and your CV to Mercè )

J. Paprocka, A. Jezela-Stanek, A. Tylki-Szymańska, S. Grunewald, Brain Sci. 11, 1– M. Izquierdo-Serra et al., Int. J. Mol. Sci. 19,

Requirements

Research Field
Neurosciences
Education Level
Master Degree or equivalent

Skills/Qualifications

We seek a motivated PhD student who is interested in the field of neurophysiology and possesses experience in neuroscience techniques, critical thinking, independence and curiosity. It is required an enthusiastic attitude, independent and team-work skills, willingness to learn as well as a good dedication to the lab work. Previous experience in a research lab will be well considered.

A high academic score is required in order to sucesfully obtain a fellowship.

Languages
ENGLISH
Level
Good

Research Field
NeurosciencesNeurosciences » NeurophysiologyBiological sciences
Years of Research Experience
1 – 4

Additional Information
Work Location(s)

Number of offers available
1
Company/Institute
Institute of Neurosciences / University of Barcelona. Faculty of Medicine and Health Sciences
Country
Spain
State/Province
Barcelona
City
Barcelona
Postal Code
08036
Street
Casanova 143
Geofield

Where to apply

E-mail

Contact

City
Barcelona
Website

Street
P. Vall d'Hebron 171
Postal Code
08035

STATUS: EXPIRED

View or Apply

To help us track our recruitment effort, please indicate in your email – cover/motivation letter where ) you saw this job posting.

---