Imaging Scientist in The Advanced Light Microscopy

hace 1 semana


Barcelona, Barcelona, España Center for Genomic Regulation A tiempo completo

The Institute


The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries.

The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

In April 2021, the CRG received the renewal of the 'HR Excellence in Research' Award from the European Commission.

This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).

Please, check out our Recruitment Policy

The role


The postholder will be working with the team at the Advanced Light Microscopy Unit (ALMU) to manage and support the imaging needs of CRG and the external research community.

The postholder will be expected to train users on routine and advanced microscopy technologies available at ALMU, daily and routine microscope maintenance, bioimage analysis, teach at courses and workshops, and occasionally collaborating in research projects.

Furthermore, develop and adapt standard protocols for training and quality control. Report and document equipment issues and initiate repairs using ALMU's RT system. Ensure that all users adhere to ALMU and CRG policies and procedures. Interact with requests and bookings through ALMU's booking system. Order with CRG's purchasing system. Prepare standard samples and maintain the wet lab area. Execute regular maintenance of Unit equipment and run routine quality control measurements to track systems' performance over time.

ALMU has over 300 users from CRG and beyond, mainly from the Barcelona area and nearby cities.

As such, the role will involve addressing research questions from a broad field, ranging from cell biology, cancer biology, marine biology, plant biology, neuroscience, biophysics and cellular biomechanics.

The postholder will be expected to operate a broad spectrum of instrumentation at ALMU covering technical capabilities for live-cell imaging, 2-photon, spectral imaging, FRET, FLIM, photomanipulation and FCS, as well as super-resolution technologies such as airyscan, STED, STED/FLIM and STORM/dSTORM, bioimage processing, analysis and data visualization.

More information about instrumentation at ALMU here.

About ALMU**ALMU is a walk-in core unit, part of CRG's Core Technologies Programme and member of Core for Life and EU-LIFE, an excellence alliance of core facilities and research institutes in Europe, and on the path to becoming a Euro-Bioimaging node. We are located in the level -1 of the PRBB building and together with our neighbours the Mesoscopic Imaging Facility (MIF) of EMBL Barcelona, we provide support and access to the full spectrum of light microscopy. We also collaborate with other research institutes in Barcelona, nationally and internationally.


The ALMU team consists of 4 dynamic and enthusiastic Imaging Scientists dedicated to assisting the research community with all aspects of Quantitative Bioimaging, including experimental design, sample preparation, acquisition, bioimage data analysis, automation and data visualization.


Our unit consists of microscope systems specifically designed for fluorescence microscopy and cover different modalities ranging from widefield and confocal to super-resolution technologies and use primarily open-source software for bioimage data analysis, including AI-based bioimage analysis.

We also run teaching courses and workshops in collaboration with CRG Training for the internal, local and international scientific community.

ALMU also develops new imaging-based methods and technologies and collaborates with the scientific community and our partner microscopy companies.

More information about ALMU here.

Whom would we like to hire?**
Professional experience

Must Have

  • Indepth understanding of optical microscopy.
  • Masters in areas such as Biophysics, Biochemistry, Bioengineering, Cell Biology or a related field. Ph.
D. is preferred but not required.

  • At least 3 years' experience in a research environment using advanced light microscopy.
  • At least oneyear experience working in a core facility environment, training users and maintaining microscopes.
  • Experience in quantitative imaging: sample preparation (live and fixed), acquisition and analysis.
  • Familiar with advanced light microscopy techniques: FRAP, photoconversion, FRET, FLIM. Familiarity with 2photon, FCS, STED, SMLM would be an asset.
  • Familiar with two or more bioimage analysis tools: Fiji/ImageJ, CellProfiler, napari, ilastik, cellpose or Huygens. Knowledge of ImageJ macro, R or Python would be an asset.

Languages

  • Strong verbal and written communication in English.
  • Knowle


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