Pharmacologist Senior Scientist

hace 1 semana


Sant Feliu de Llobregat, Barcelona, España Almirall A tiempo completo

Date:29 Aug 2023

Location:
SFEL - R&D SANT FELIU DE LLOBR, ES, ES - Spain

Company:
Almirall

Mission:

Tasks and Responsibilities:

Key responsibilities include but are not limited to:

  • Develop robust new in vivo humanized models in dermatological disease using best available technologies and equipment.
  • Contribute to discovery and development projects for small molecules and antibody therapeutics by conducting in vivo efficacy, PK/PD studies utilizing syngeneic mouse and humanized models
  • Maintain cell lines using standard cell culture techniques in support of in vivo studies.
  • Use standard immunology techniques (MACS, FACS, ELISA) to support in vivo and ex vivo analysis of cells from animal tissues or human skin samples.
  • Assay execution, maintaining the quality of assays, data analysis and publication.
  • Active engagement across drug discovery activities and on project teams.
  • Work in a highly crossfunctional environment to align biologics and small molecules strategy from early project initiation.
  • Write and or review technical and study reports
  • Present scientific results at team and staff meetings
  • Strong technical and computational abilities.
  • Ability to work in a matrixed, collaborative environment with shared resources and effectively communicate within and across teams.
  • Ability to work independently and prioritize work assignments.

Education & Experience:

  • Ph.
D. and/or MSc. in relevant scientific area and mínimally 4 years of hands-on in vivo pharmacology experience in academic or industry environment. Immuno-dermatology or dermato-oncology experience is a plus.

  • FELASA license or equivalent is a must.
  • Proficiency in mouse handling and dosing (intradermal, intralesional, topical intraperitoneal, subcutaneous, intravenous, and oral gavage)
  • Demonstrated ability to independently conduct dermatology mouse studies is a plus.
  • Experience in developing and conducting syngeneic, xenograft, and humanized mouse models
  • Excellent aseptic cell culture technique for handling human and murine primary cells and cancer cell lines
  • Strong attention to detail.
  • Excellent recordkeeping abilities.
  • Excellent interpersonal and communication skills.
  • Demonstrated proficiency in the use of software tools to support data analysis (e. g., Prism, FlowJo, Word, Excel, and Powerpoint)
  • Ability to critically interpret and effectively present data
  • Adaptability to shifting priorities and changing work assignments

Values:

  • Care
  • Courage
  • Innovation
  • Simplicity


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