Postdoctoral position

hace 3 meses

Barcelona, España Centre de Regulació Genòmica (CRG) A tiempo completo

The role

We are seeking a postdoctoral researcher to develop a project focused on understanding whether the nuclear localization of metabolic enzymes can be used to predict cancer stage, grade, and response to therapy. The selected candidate will analyse mass spectrometry (MS) data to determine the enrichment of metabolic enzymes in the chromatin compartment. Such data will be validated with immunohistochemistry and immunofluorescence (with the help of a technician) and the selected candidate will develop a pipeline for image analysis and integration of different markers together with subcellular localization of selected metabolic enzymes. The goal of this project is to develop novel guidelines for patient stratification based on the subcellular localization of enzymes.

About the lab

Our laboratory specializes in high-throughput image analysis, subcellular proteomics, transcriptomics, genetic screening, bioinformatics and cell and molecular biology techniques. We are a group of about 10 people from different cultures and countries. We are part of the genome biology department at the CRG, and we aim to understand why metabolic enzymes localize to the nuclear environment and participate in specific chromatin functions.

Whom would we like to hire?

Professional experience

Must Have

You have proven experience in bioinformatics
You have experience image analysis, omics analysis, MS analysis
You have a first author publication
You are eligible for international or national fellowship programs, such as:
(deadline 14th of February 2025)
(deadline 11th of September 2024)
(expected deadline January 2025)
(expected deadline November 2024)

Desirable but not required/ Nice to have

You have knowledge of cancer biology, in particular breast cancer

Education and training

You have a PhD in biological sciences, Molecular Biology, Computational Biology, Bioinformatics, or related fields

Languages

You are proficient in English (oral and written)

Competences

Strong analytical and problem-solving skills
Ability to perform tasks with minimal supervision
Have the drive and commitment to produce high quality experimental results
Strong organizational skills
Ability to work as part of a team
Strong academic writing skills
Collegiality
Punctuality in delivering results

The Offer – Working Conditions

Contract duration: Technical and scientific activities contract – estimated duration 1 year with possible renovation
Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales
Target start date: 1st November (2024)

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website’s .

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

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