Senior Scientist – AI Agent Systems for Drug Discovery

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at

Job Function
Data Analytics & Computational Sciences

Job Sub Function
Data Science

Job Category
Scientific/Technology

All Job Posting Locations:
Cornellà de Llobregat, Barcelona, Spain, Madrid, Spain

Job Description
J&J IM develops treatments that improve the health and well-being of people worldwide. Research and development areas encompass oncology, cardiovascular and retina disorders, immunology, and neuroscience. Our goal is to help people live longer and healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market – from patients to practitioners and from clinics to hospitals. To learn more about J&J IM, please visit

Johnson & Johnson Innovative Medicine (J&J IM) is recruiting for the role of
Senior Scientist – AI Agent Systems for Drug Discovery
. This position has a primary location of
Barcelona, Spain
. The secondary location is
Madrid
. This is a hybrid role.

The Machine Intelligence (MI) team within Data Science and Digital Health (DSDH) AI/ML is looking for a mission-driven Senior Scientist to help shape the future of autonomous AI in drug discovery and development. You'll work with Large Language Models (LLMs) and advanced data science techniques, harnessing massive datasets spanning scientific literature, omics, and biomolecular knowledge. Your work will directly accelerate how we discover therapeutics and advance them to clinical trials - making reasoning agents faster, more accurate, and more reliable. Key focus areas include multimodal reasoning, agent robustness and uncertainty, agent memory architecture, and agent motivation frameworks.

Key Responsibilities

• Develop and optimize multimodal reasoning systems that integrate scientific literature, omics data, chemical information, and structured data to derive actionable conclusions
• Build novel agent memory architectures to enable persistent knowledge retention and context-aware decision-making across extended discovery workflows
• Prototype and evaluate new approaches for uncertainty quantification and reliability assessment in AI-driven scientific reasoning
• Serve as a domain expert within the field by articulating to team members emerging approaches and methodologies within the AI/ML with a clear understanding of their practical applications
• Benchmark agent performance against human expert decisions and existing computational methods and demonstrate ability to publish results in leading journals and conferences

Required Qualifications

• A Ph.D. degree in AI/ML or related field (e.g., computer science, machine learning, data science, applied mathematics, statistics) with at least two (2) years working experience
• Knowledge in advanced mathematics areas such as Bayesian inference, uncertainty quantification, information theory, causal inferencing, graph neural networks, etc.
• Proficiency with open-source agentic frameworks (e.g., LangGraph, DSPy, mem0, etc.) and deep learning frameworks (e.g., PyTorch, Tensorflow, etc.)
• Proficiency in one or more programming languages – preferably Python
• Positive and motivated demeanor with the ability to work both independently and in a diverse, multi-disciplinary team

Preferred ("nice-to-have") Qualifications

• Understanding of drug discovery pipeline and familiarity with biological data types
• Strong understanding of statistics and applicable methods to validate model performance
• Familiarity with cloud hosting solutions (ex. AWS and/or Azure)

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, and will not be discriminated against on the basis of disability.

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