Senior/principal) Scientist, Neuroscience, Immunology, and Cv

**Working with Us**
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

We seek a creative and passionate computational biologist with a strong background in clinical data analysis to join the Neuroscience, Immunology, and Cardiovascular (NIC) Translational Informatics team within Informatics and Predictive Sciences (IPS). In this role, you will use machine learning and advanced statistical approaches to analyze high-dimensional data from late-stage clinical trials and longitudinal patient cohort profiling.

In support of an exciting late-stage cardiovascular, immunology and neuro portfolio, your responsibilities will include patient subgroup stratification, biomarker discovery for treatment response and resistance, and mechanistic analyses to support Life Cycle Management (LCM) and indication expansion. You will also contribute to reverse translation, leveraging clinical insights to inform early research and drive bedside-to-bench innovation beyond the current portfolio. Your work will directly impact the development of novel therapies for patients with cardiovascular diseases (e.g. Heart Failure with Preserved Ejection Fraction), Immunology and Neuroscience.

**Key Responsibilities**
- Analyze high-dimensional datasets from late-stage clinical trials and multi-modal real-world datasets from commercial partners, pre-competitive consortiums, and public resources.
- Work with diverse data modalities, including clinical data (ADaM/SDTM), high throughput proteomics (e.g., Olink, SomaScan), Whole Genome Sequencing, genotyping array, RNA-Seq and multiplex flow cytometry.
- Communicate findings and recommend follow-up actions in multiple settings (including 1:1, seminars, and team meetings). Participate in authorship of scientific reports and present methods and conclusions to publishable standards.

**Basic Qualifications**
- Bachelor's degree with 6+ years of academic/industry experience, or
- Master's degree with 4+ years of experience, or
- PhD with 2+ years of experience in computational biology or a related field

**Preferred Qualifications**
- PhD from a recognized institution in a quantitative field such as computational biology or related
- Experience analyzing clinical data from interventional clinical trials, including integration of structured clinical endpoints (e.g., ADaM/SDTM), biomarker data (e.g., lab measures), and longitudinal assessments to support pharmacodynamic analyses, as well as the identification of predictive, prognostic, or surrogate endpoint biomarkers.
- Experience analyzing and integrating high-dimensional molecular datasets such as multi-omics (e.g., RNA-seq), single cell (scRNA-seq), genome-wide genotyping array, or spatial transcriptomics datasets
- Advanced hands-on knowledge of at least one high-level programming language such as R or Python for computational and reproducible research practices
- Track record (such as scientific publications) in driving and advancing research projects/programs with computational approaches
- Strong oral and written communication skills

Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to gender identity, race, color, religion, sexual orientation, national origin or disability.

**Uniquely Interesting Work, Life-changing Careers**

**On-site Protocol**

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

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