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2025 69 open Call for Msca

hace 3 semanas


Badalona, España IGTP A tiempo completo

**JOB DESCRIPTION**:
**MAIN RESPONSIBILITIES**:
The research project will focus on the comprehensive characterization of the pathogenic DMPK repeat expansion associated with myotonic dystrophy type 1 (DM1), using cutting-edge long-read sequencing technologies. The specific tasks and responsibilities include:

- Design and execution of experiments involving long-read sequencing to analyse repeat length, sequence interruptions, somatic mosaicism, and methylation patterns at the DMPK locus.
- Bioinformatic processing and analysis of long-read data, including the development or adaptation of pipelines to study repetitive and epigenetically regulated regions.
- Integration of multi-omics data, including transcriptomic and metabolomic datasets, to investigate disease mechanisms and identify potential biomarkers.
- Collaboration with clinical and experimental teams to ensure translational relevance of the findings and contributions.
- Preparation of scientific publications, conference presentations, and reports derived from the project outcomes.
- Engagement with the broader MSCA network, including participation in training activities and workshops.

**QUALIFICATIONS AND EXPERIENCIE**:
**Q**UALIFICATIONS AND EXPERIENCE**:

- Supported fellows: Must be in possession of doctoral degree. At the call deadline (10-09-2025), supported researchers must have a maximum of 8 years full time equivalent experience in research, measured from the date that the researcher was in a possession of a doctoral degree and certified by appropriate documents.
- Nationality: Any.
- Mobility: The researcher must not have resided or carried out his/her main activity (work, studies, etc.) in the country of the host organization for more than 12 months in the 3 years immediately prior to the deadline.
- Researchers wishing to reintegrate from a third country must either be based in a third country at the call deadline, or have moved directly from a third country to an EU Member State or Horizon Europe Associated Country within the last 12 months before the call deadline.
- Must be fluent in English (both written and spoken)

We are looking for talented and innovative scientist with a strong background in molecular genetics, genomics, bioinformatics, and/or neurobiology. We seek highly motivated researchers capable of working both independently and as part of a multidisciplinary team.
- Long-read sequencing technologies.
- Analysis of repetitive DNA regions, structural variants, or somatic mosaicism.
- Transcriptomic or epigenomic profiling.
- Multi-omics data integration (transcriptomics, metabolomics, epigenomics).
- Bioinformatics and data analysis in a Linux/Unix environment.
- Rare disease research, especially in neuromuscular or neurogenetic disorders.

**WHAT WE OFFER**:
**Contribution for the recruited researcher per person monthly**:

- Living allowance: 5990€
- Mobility allowance: 710€
- Family allowance (if applicable): 660€ x % covered by the beneficiary
- Long-term leave allowance (if applicable): 6700€
- Flexible payment (childminding vouchers).
- 23 days holiday and 5 days for personal matters +2 days for Easter + 2 days for Christmas.
- Training capsules by the company.
- Be part of an excellent multidisciplinary research centre with the HRS4R badge.
- Location on the Can Ruti Campus, a first-class translational research environment in the Barcelona area, in a very stimulating scientific environment. The IGTP offers a supportive, friendly and collaborative ecosystem to promote professional development and help you achieve your research goals.

**FOR MORE INFORMATION**:
**HOW TO APPLY**:

- Motivation letter explaining their interest in the position.
- Short CV (max 2 pages)
- Contact of 2-3 references.

Applications will be evaluated in accordance with the guiding principles and objectives of the supply systems, following the process described below:

- ** Curricular evaluation**: analysis of the curriculum vitae to assess aspects related to training, professional career and experience in positions related to the job position under selection.

Applications that do not meet the requirements, that are not included in the cases foreseen or that are not processed in accordance with the established procedure will not be considered in the selection process.

**DEADLINE FOR APPLICATIONS**:

- Deadline of the next call for proposals for MSCA - Postdoctoral Fellowships is **September, 10th 2025**.
- You can send this Expression of interest to the contact person **before 15/07/2025**:
**About us**:
The Germans Trias i Pujol Research Institute (IGTP) is a public research centre located in Badalona. Its main objective is to increase scientific knowledge in order to transform it into solutions to improve the health and medical care of patients and the community.

The Institute is associated with one of the major university hospitals in the Barcelona area, the Germans Trias i Pujol Hospital, and is part of the Can Ruti biomedical campus. I