Postdoctoral Position in Tumour Model Design and

**Published**:10/10/2024

**Deadline**:17/11/2024
**Envisaged Job Starting Date**:
January 1st, 2025

The position is directly linked to the project _BIOSCAFFONC_ “3D printed BIOsensing cellular SCAFFolds for precision ONCology”, selected for funding by the Spanish Research Agency (AEI). BIOSCAFFONC aims to develop 3D printed scaffolds suitable for the development of breast cancer in vitro models with in situ sensing capabilities. The project will simultaneously follow two lines of investigation, namely the development of biocompatible materials to mimic the tumour microenvironment (TME), and of chiroptic gold nanoparticles (NPs) as substrates for sensing of biomolecules or physical changes related to the TME. The ultimate goal is the development of non-invasive biosensing techniques via in situ spectroscopic means, combining knowledge from the fields of biomaterial design, in vitro organoid models, advanced plasmonic NP synthesis methods, and chiroptical related spectroscopy, amongst others.

The main tasks of the position are:

- Design and synthesis of biocompatible materials, suitable for 3D printing and scaffold fabrication.
- Cell culture of organoids, including authentication of cell phenotype.
- Design of optimal cancer cell and tumor microenvironment, including cell media optimization in heterogeneous cell cultures.

Key responsibilities include conducting independent and collaborative research, data processing and analysis, and preparation of presentations, scientific manuscripts, and internal reports. Proactive communication with peers and supervisors is essential.

The project is to be carried out at **CIC biomaGUNE**, a vibrant multidisciplinary and international research institute in San Sebastian, Spain. **CIC** biomaGUNE**_ _**has established a state-of-the-art research program at the interface between the chemical, biological and physical sciences. It offers excellent working conditions and is well equipped with instrumentation and facilities.

**Required Education Level**:
A PhD in a relevant area of Biotechnology, Biomaterials Science, Biology, Biochemistry, Bionanotechnology, or related areas.

Experience in the fields of biomaterial design, polymer synthesis, rheology, 3D bioprinting, advanced 3D cell culture, organoid culture, fluorescence confocal microscopy, proteomics. and/or SERS is highly desirable. Prior experience in the development of in vitro cancer models will be considered an advantage.

**Required Skills/Qualifications**:
**Duration**:
**Project Funding**:
BIOSCAFFONC - PID2023-151281OB-I00 - (Spanish Research Agency - AEI)

**Informal Inquiries**:
**Equal opportunities Policy**:
CIC biomaGUNE is proud to be an equal opportunity employer and applicants will receive consideration for employment without regard to: age, color, disability, gender, national origin, race, religion, sexual orientation, gender identity, or any other classification protected by European, national, or local law.

**Open Transparent and Merit Based Recruitment Policy**:
**How To Apply**:
**_About CIC biomaGUNE:_**
- CIC biomaGUNE, located in the Science and Technology Park of Gipuzkoa (Donostia-San Sebastián), is a leading research center in the area of bionanomaterials, molecular imaging and _synthetic bioengineering_ and counts with more than 160 people from 27 countries. The activity of CIC biomaGUNE is conducted by a team of 12 international and dynamic research groups, supported by flexible and efficient management teams and a unique research infrastructure including the Molecular Imaging Facility, one of the biggest preclinical imaging research infrastructures in Europe._
- CIC biomaGUNE maintains a vibrant weekly scientific seminar program by visiting leading scientists. Additional training in soft skills and technologies covered by the CIC biomaGUNE technical platforms is offered to researchers within the in-house training program._
- CIC biomaGUNE is committed to develop a HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code). Please check out the Human Resources Strategy for Researchers - _HRS4R at CIC biomaGUNE and the OTM-R Policy._