Facility Manager Fluid Biomarker Facility

C/Wellington 30

08005 Barcelona

T +34 93 316 09 90

**Facility Manager**
**Fluid Biomarker facility in the Barcelonaβeta Brain**Research Center**

**About the employer**

The Barcelonaβeta Brain Research Center (BBRC) is a research center dedicated to the prevention of

Alzheimer's disease and the study of cognitive functions affected in healthy and pathological aging. It was

created in 2012 by the Pasqual Maragall Foundation, with the support of the Pompeu Fabra University.

The mission of the BBRC is to provide innovative solutions to decipher and prevent biological changes and

cognitive dysfunction associated with neurodegenerative diseases. Due to the aging of the world

population, these diseases constitute a global challenge, since for example, dementia can reach epidemic

levels in 2050, with a forecast of more than 150 million people affected, if is not found a way to prevent

its appearance and development.

The BBRC received the HR Excellence in Research award (HRS4R) granted by the European Commission; a

recognition that shows its adherence to the principles of the European Charter for Researchers and the

Code of Conduct for the Recruitment of Research Staff. The center offers a **stimulating and favorable**
**working environment** in accordance with the Charter and Code, which describe the rights and

responsibilities of researchers and their employers, and contributes to the **creation of a transparent,**
**attractive and open ecosystem** at international level.

Pasqual Maragall Foundation, Pompeu Fabra University and “la Caixa” Foundation are permanent

members of the BBRC Board. The center is affiliated and located in the Ciutadella Campus of the Pompeu

Fabra University of Barcelona, in a building inaugurated in 2016. The BBRC headquarters has excellent

technical facilities, including a 3TMR scanner dedicated to research, and spaces for conducting Clinical

Trials and EEG. State-of-the-art scientific facilities, effective management and continuous high-standard

peer-review evaluation are the BBRC core proceedings to ensure achieving world-class research results.

BBRC is also part of the Barcelona Biomedical Research Park (PRBB), a large research facility that hosts

other seven different research institutions related to biomedical research, including the Center for

Genomic Regulation (CRG), the Hospital del Mar Medical Research Institute (IMIM), the Department of

Experimental and Health Sciences of the Pompeu Fabra University (CEXS-UPF), the Institute of Evolutionary

Biology (IBE CSIC-UPF), the Barcelona Institute of Global Health (ISGlobal) and the Barcelona site of the

European Molecular Biology Laboratory (EMBL), among others, in a multidisciplinary, collaborative and

stimulating international environment in close contact with a clinical setting, thus conducive to

translational research.

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Registre de Fundacions Privades de la Generalitat de Catalunya N. 2765 30/05/2013 NIF/VAT: G65895401

C/Wellington 30

08005 Barcelona

T +34 93 316 09 90

**About the project**
The development of blood based biomarkers in the field of Alzheimer’s disease and related

neurodegenerative disorders have become a reality. Our institution has recently established a Fluid

Biomarker Facility equipped with different analytical technologies including the most advanced

ultrasensitive biomarker platforms. We expect to incorporate additional cutting-edge technologies to

perform high-multiplex, high-throughput protein biomarker measurements. The new Fluid Biomarkers

Facility will offer fluid biomarkers measurements and research support, in collaboration with the “Fluid

Biomarkers and Translational Neurology Research Group” (Group Leader: Marc Suárez-Calvet), to

researchers at the PRBB, other academic or research institutions, health centers and industry. We envision

intense collaborations with all relevant stakeholders, both international and local, public and private, to

accelerate research in AD and neurodegeneration. BBRC has the goal of becoming a reference lab in blood

biomarkers for AD and other neurological diseases.

The facility will perform existing biomarkers assays in cerebrospinal fluid, blood and other fluids (_e.g._,

saliva, urine). The new Biomarkers Facility will also develop, validate and implement novel fluid biomarkers

that will improve the diagnosis of AD and other age-related neurodegenerative diseases in their earliest

treatment effectiveness, or using them as surrogate markers in clinical trials. The Biomarkers Facility will

assay development, and, finally, clinical implementation. We aim to generate a better understanding of

the pathophysiology of neurodegenerative diseases and to provide biomarkers that are relevant for clinical

purposes.

**About the job**
The Barcelonaβeta Brain Research Center (BBRC) seeks a manager for the Fluid Biomarkers Facility.

wide range of analytical platforms will be employed depending on specific projects (Simoa,