Phd Student

The **Josep Carreras Leukaemia Research Institute** (IJC) is a non-profit research institute based in Barcelona dedicated to advancing the understanding of leukemia and related disorders, in collaboration with the University of Barcelona and the Autonomous University of Barcelona. The IJC has laboratories in 5 clinical campuses: i) Hospital Clínic, ii) Hospital de Sant Pau and iii) Hospital Germans Trias Pujol iv) Hospital del Mar and v) Hospital Josep Trueta Girona. IJC serves as a collaborative center for basic researchers and physicians to work together on fundamental clinical and biological aspects of leukemia. The IJC offers an excellent work environment based on a multidisciplinary fusion of state-of-the-art ideas and facilities.

The Josep Carreras Leukemia Research Institute Can Ruti is looking for a **PhD student** for the Cancer heterogeneity and hierarchies group led by **Dr. Veronica Rodilla**.

**Research Description**

Cancer is a heterogeneous disease with a cellular hierarchical organization poorly explored in many tumor subtypes and, in some cases, hierarchical relationships between stem cells, progenitors and differentiated cells remain unsolved due to the high degree of cellular plasticity, which allows cells to switch between different cellular stages.

Since 2020, we focus our efforts in understanding cellular organization within tumors, changes in cell fate, specific cellular behavior upon different therapies and interactions between different tumor cell populations and with their microenvironment. In the era of the next generation sequencing, we use _in vivo_ and _ex vivo_ alternative models to reach a comprehensive cellular picture beyond genetics.

**What we need**

**General skills**
- Committed scientist with a competitive scientific record and experience in cellular and molecular biology, and breast tumor malignancies.
- A high level of motivation and interest in biomedical research.
- Good communication skills.
- Fluent in English

**Technical skills**
- Degree in Biology or Biochemistry
- MSc in Experimental medicine (or similar) with a TFM related on oncology
- Demonstrable experience (through communications to congresses or participation in research articles) in: cell cultures, qPCR, flow cytometry, drug titration and functional assays for tumor progression.
- Certificate for working with animals (Functions A, B and C).
- Previous experience with murine models will be highly valued

**What we offer**
- 22 months funded PhD position. (Contract funded by Fundación Asociación Española Contra el Cáncer (FAECC) under call Lab AECC 2021, Ref**:LABAE211626RODI**)
- Be part of a young, collaborative and international work environment with cutting-edge technologies and interdisciplinary teams of scientists, including experts in medicine, immunology, genomics and bioinformatics.
- Core facilities of the IJC include flow cytometry, genomics, proteomics and the single-cell unit.
- An exciting and innovative research project.
- The stimulating environment of the Barcelona metropolitan area.

**Deadline for Applications**

**Who we are?**

The European Commission awarded the IJC the HR Excellence seal in July 2019. The IJC continues to work to maintain its policies in line with the Charter and Code principles. The HRS4R has the main objective of ensuring that research centers of excellence implement and respect the requirements of the European Charter for Researchers and the Code of Conduct for hiring researchers (from here on referred to as the Charter and Code) within their human resources policies. This EC initiative aims to promote training, professional development, and mobility for all European scientists. The IJC supports these values and principles, which will not only serve to strengthen its internal policies but will actively stimulate excellent research and firmly situate the organization as an institution with a stimulating working environment that favors the development of its scientists. IJC is an equal opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, national origin, disability, and other legally protected characteristics.