Senior Statistician Ii

The Senior Statistician II brings extensive experience in the pharmaceutical industry, working independently on design, delivery, and interpretation of preclinical studies, regulatory submissions, and commercialization. This role involves performing and communicating results of complex analyses, guiding less experienced staff, and developing innovative statistical ideas and approaches. The individual will contribute significantly as a competent collaborator across functions.

**Accountabilities**:
The Senior Statistician II may work directly within a project and/or support statistical methodological advances. The accountabilities for supporting projects directly are:

- Provide statistical expertise for complex design and interpretation for preclinical or clinical programmes, high-level internal governance committees, regulatory submissions, and/or commercialization.
- Analyze internal and external information, perform modeling and simulation to inform design decisions and develop decision criteria.
- Develop a Statistical Analysis Plan for complex studies and/or project deliveries.
- Act as a coach/guide for less experienced statisticians in the production of analysis, supporting graphics, and analysis tables for study reports, Global Medical Affairs studies, or publications.
- Analyze, interpret, summarize, and communicate results of complex studies.
- Contribute to regulatory submissions including specification of overview documents and response to regulatory questions.
- Identify opportunities to improve methodology and provide practical solutions for problems.
- Contribute to the development of best practices to improve quality, efficiency, and effectiveness.- Accountable for the quality of their statistical work; provide discipline-specific understanding, insight, and constructive challenge, and take ownership of development needs, seeking coaching or training opportunities.
- The accountabilities for supporting statistical methodological advances are:

- Under guidance of a more experienced statistician, produce pragmatic solutions often within a tight time scale where the emphasis is to deliver first, then refine and develop solutions thereafter.
- Draft statistical analysis plans for complex studies.
- Provide consultancy within area of expertise to fellow statisticians working within therapeutically aligned statistics groups, as well as medical scientists and other key roles across the business.
- Investigate and improve statistical approaches, establish standards and best practices, develop and implement new methodology interacting with external scientists.
- Identify new areas where we can add value, developing collaborative relationships with the external scientific/academic community and maintaining academic links.
- Contribute to or lead the development of a process improvement and/or capability area within the Department.
- Develop a strong understanding of the pharma business/AZ ways of working.
- Communicate research and results internally and externally through participation at conferences and journal publications.

**Essential Skills/Experience**:

- MSc/PhD in Statistics, Mathematics (containing a substantial statistical component), or recognized equivalent to stats MSc
- Competent statistical programmer (SAS and R)
- Knowledge of key technical and regulatory requirements
- Experience of design, analysis, and reporting of preclinical or clinical studies in more than one setting
- Communication skills
- Collaboration and team working skills

**Desirable Skills/Experience**:

- Collaboration required

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace, and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, we follow the science with curiosity and determination. Our commitment to Oncology R&D has led to significant breakthroughs with seven new Oncology medicines since 2013. We continuously push boundaries by fusing cutting-edge science with advanced technology. Our collaborative research environment unites academia and industry to expedite research in some of the hardest-to-treat cancers. Join us to build a rewarding career dedicated to improving millions of lives.