Vac 42 2025 - Senior Postdoctoral Researcher

The Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive **cancer research center** dedicated to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases. It was created in 2010, and since then has experienced an exponential growth.

The IJC is also part of the network of Excellence Research Centers of Catalonia **(CERCA)** and was accredited as a **Severo Ochoa Center of Excellence** by the Ministry of Science, Innovation, and Universities in 2024. Since 2018, the Institute has also been accredited by the Scientific Foundation of the Spanish Association Against Cancer **(FCAECC)** Additionally, IJC is one of the centers integrated into the Institut de Recerca Germans Trias i Pujol (IGTP) accreditation as Accredited Health Research Institute (IIS) by the Carlos III Health Institute **(ISCIII)**.

The IJC's main headquarters is located within the Can Ruti Biomedical Campus, alongside other leading biomedical institutions, providing direct access to cutting-edge scientific and technological facilities, as well as complementary community services. The IJC has **six locations integrated into reference hospitals**: Hospital Germans Trias i Pujol, Hospital Clínic, Hospital Sant Pau, Hospital Josep Trueta, Hospital del Mar and Hospital San Joan de Déu. This facilitates close collaboration between basic and clinical researchers, fostering translational research that integrates basic science with clinical practice in clinical settings.

We are looking for a **Senior Postdoctoral Researcher**to join the Acute Lymphoblastic Leukemia (ALL) Group led by Dr. Josep Mª Ribera at our institute.

**RESEARCH DESCRIPTION**

Our research is focused on Acute Lymphoblastic Leukeamia (ALL) disease, including B-cell precursor and T-precursor ALL. We want to resolve questions that require a full range of research from from basic to clinical. We aim to provide the physician with new tools, by using basic research data that will have an impact on healthcare, in order to improve survival rates in patients with this type of leukaemia.

The group’s current research is divided into two main areas, according to the two main subtypes distinguished in ALL:

- Precursor B-cell acute lymphoblastic leukaemia (BCP-ALL): BCP-ALL is the most prevalent ALL subtype and accounts for 75% of ALL cases. Although it is a highly heterogeneous disease at genetic level, different cytogenetic subtypes have been identified and, more importantly, their prognosis has been clearly established in many clinical trials. This has allowed clinicians to stratify patients according to their genetic profile to schedule intensive or less intensive treatments.
- T-cell acute lymphoblastic leukaemia (T-ALL): T-ALL is the least common ALL subtype (25% of adult ALL cases), and the most complex and heterogeneous at genetic level, with a dismal prognosis. to improve the survival rate of patients with T-ALL, we first need to obtain detailed and relevant molecular information to accurately define the risk and thus decide on the treatment.

**MAIN RESPONSABILITIES**
- Responsibility and management of the T-ALL research line.
- Support to internal and external projects.
- Research staff management.

**WHAT WE NEED**
- PhD in Life Sciences
- Experience in Research projects, at least of 8 years.
- Experience in T-ALL research line
- Proficient in writing and speaking in English.
- Leadership and teamworking
- Communication skills
- Proactivity, initiative and solving problem’s ability
- Organized, self-motivated, and enthusiastic.
- High motivation biomedical research
- Capacity for analysis and supervision.

**WHAT WE OFFER**
- Temporary contract (3 years)
- Full time contract.
- To manage a strategic platform in the institute
- Working in the mixed basic and clinical research environment of the Josep Carreras Leukaemia Research Institute.
- The opportunity to contribute to cutting-edge translational research projects in the stimulating environment of the Josep Carreras Leukaemia Research Institute.
- The stimulating environment of the Barcelona metropolitan area.

**DEADLINE**

**WHO WE ARE?**

**_ What makes us different?_**:
The mission of the Josep Carreras Institute is to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases.
The IJC’s vision is to be a world-class reference and excellent research multicampus that contributes to the improvement of results, and the cure of patients affected by leukemia and other malignant hemopathies, through innovation, sustainability, social responsibility, talent, and professional experience.

**_ HR Excellence_**:
In 2019, IJC was honored with the “Human Resources Excellence in Research Award” by t