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ADVANCED TECHNICIAN IN PROTEOMICS
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Job description The Omic Sciences Department carries out its activities using state-of-the-art infrastructures at the Centre for Omic Sciences (COS) , a unique center equipped with the latest metabolomics, proteomics, transcriptomics, and genomics technologies. It offers a comprehensive range of biomarker research services across health, food, and environmental sectors, from project design support to the analysis and integration of data obtained from various omics technologies. We are seeking an experienced and highly skilled Specialist Proteomics researcher to join our cutting-edge Proteomics Platform. The successful candidate will work closely with researchers and industry partners to advance proteomics methodologies, particularly in ultra-sensitive quantitative proteomics, post-translational modifications (PTMs), and integrative multi-omics approaches. RESPONSABILITIES As a valued member of our team, your role encompasses several critical dimensions: • Develop and optimize new nanoLC-MS/MS methods for proteomics analysis.• Perform sample preparation, protein digestion, mass spectrometry acquisition, and data analysis for proteomics research.• Maintain and troubleshoot high-end mass spectrometry instrumentation, ensuring high-quality results.• Implement quality control (QC) and validation protocols for proteomics workflows.• Develop strategies for protein identification, annotation, and quantification, using advanced data processing tools (e.g., Proteome Discoverer, MaxQuant,,…).• Actively participate in scientific publications, documentation, and standardization of protocols.• Support research projects and collaborate with national and international partners.• Assist in lab organization, supply management, and maintenance of proteomics databases. WHAT WE OFFER • The opportunity to work on cutting-edge biomedical projects with high impact.• A collaborative and interdisciplinary environment with national and international partners.• Access to state-of-the-art LC-MS/MS technologies.• Opportunities for career development and training in proteomics and analytical sciences. If you are passionate about mass spectrometry-based proteomics and want to be part of a leading research team, we encourage you to apply Requirements Qualifications: • PhD, Master’s, or Bachelor’s degree in Analytical Chemistry, Biochemistry, Biomedical Engineering, or a related field. Knowledge and Experience: • Extensive experience in mass spectrometry and chromatography (LC-MS/MS, HRMS) applied to proteomics.• Strong background in proteomics workflows, including bottom-up and top-down proteomics, DIA, and label-free quantification.• Proficiency in software for MS data processing (e.g., MaxQuant, Proteome Discoverer, Skyline,…).• Experience in data preprocessing.• Experience in mass spectrometry instrument maintenance and troubleshooting.• High motivation for research and scientific documentation/publication.• Excellent organizational skills, teamwork ability, and problem-solving skills.• Fluency in English (B1 or higher) and proficiency in Spanish and Catalan. Additional Valued Skills: • Experience in protein sample preparation from biofluids or tissues.• Experience in advanced techniques such as glycoproteomics and PTMs analysis• Familiarity with standard operating procedures (SOPs) and quality management systems.• Knowledge of machine learning applications in proteomics, and statistical analysis (univariate/multivariate), and bioinformatics tools
