Senior Clinical Project Manager

Global Trial Operations (GTO) Manager The Global Trial Operations (GTO) Manager leads the strategic planning execution and ongoing optimization of global clinical trials. This role integrates feasibility strategy and operational leadership with advanced data analysis cross-functional collaboration and alignment across the enterprise. The GTO Manager plays a critical role in delivering high‑performing patient‑centric trials by aligning scientific objectives with operational strategies, real‑world data insights, and commercial goals. Responsibilities and Tasks Lead portfolio‑wide feasibility strategy and optimization efforts across studies ensuring timely enrollment and risk‑adjusted planning. Oversee enrollment forecasting using internal tools and collaborate with study teams on re‑forecasting when performance trends deviate. Perform root cause analysis for underperforming trials and recommend optimized country and site scenarios in coordination with the Feasibility team. Develop scalable methodologies for global site selection aligned with patient access regulatory readiness and future commercialization potential. Contribute strategic input during indication and country allocation planning to enhance portfolio execution. Embed trial optimization into early clinical development discussions to improve long‑term success rates. Partner with Commercial Business Information Services to integrate real‑world data and enterprise analytics into feasibility and site planning. Provide robust data intelligence packages on indication landscape recruitment benchmarks trial competition and market trends. Stay current with AI/ML trends and drive innovation through the application of predictive analytics and optimization algorithms. Establish and monitor key performance indicators (KPIs) to measure the impact of trial optimization initiatives and continuously refine approaches. Align with IT and systems stakeholders to ensure enrollment forecasting integrates into enterprise planning platforms and data lakes. Collaborate with internal and external vendors to ensure tools, systems, and methodologies are optimized for trial execution. Develop standardized SOPs and workflows that govern data use, feasibility processes and optimization frameworks. Lead change management efforts to embed data‑driven optimization practices across clinical teams and therapeutic areas. Provide training and oversight for business users on new forecasting tools, dashboards and system enhancements. Champion adoption of new tools and methodologies fostering a culture of continuous improvement. Mentor and lead a global team responsible for optimization initiatives. Support team development through performance coaching, growth planning and cross‑functional collaboration opportunities. Requirements Bachelors or Masters degree in Life Sciences, Public Health, Biostatistics or related field; PhD/MD/PharmD a plus. Senior Manager Level with 12 years of experience in clinical development or clinical operations with at least 5 years in a global strategic leadership role. Associate Director Level with 20 years of experience in clinical development or clinical operations with at least 10 years in a global strategic leadership role. Minimum 1 year of experience managing direct reports and leading cross‑functional initiatives. Proven experience with country and site selection feasibility assessments and enrollment planning. Strong knowledge of real‑world data tools (e.g. CTMS, Citeline, TA Scan, TriNetX, H1) and other analytics platforms. Demonstrated ability to lead portfolio‑level planning and integrate operations with commercial strategy. Expertise in business intelligence data lake architecture and system integrations. Strong communication, stakeholder engagement and problem‑solving skills. Demonstrated ability to drive innovation, continuous improvement and scalable operational excellence. Key Skills Business Development Project Management Methodology Project / Program Management PMBOK Waterfall Wastewater Construction Management Project Management Project Management Software Microsoft Project Budgeting Contracts Employment Type : Full‑Time #J-18808-Ljbffr