3-Years Phd Position

hace 1 día


Madrid, España CSIC A tiempo completo

OverviewAntimicrobial Discovery Lab at Instituto de Química Física Blas Cabrera (IQF-CSIC) offers a 3‑year PhD position. The project is part of the international Open Source Antibiotics consortium, aimed at identifying inhibitors that target multiple enzymes essential for bacterial survival.Key ResponsibilitiesStudy Mur ligases (MurC, MurD, MurE, MurF) from Mycobacterium tuberculosis and other enzymes for inhibitor screening.Explore experimental conditions that favor homogeneous conformations and facilitate crystallisation in the presence of inhibitors.Generate crystallographic structures of Mur ligases in complex with relevant inhibitors for rational drug design.Periodically evaluate progress and potentially incorporate alternative projects as required.Optimize protocols, study protein–ligand interactions, and analyse resulting data, requiring intensive specialised work.Participate in a training programme covering basic biochemical techniques, protein expression and purification, crystallography, and biophysical, enzymological and computational methods.Prepare and present scientific results as part of a PhD thesis.Qualifications & RequirementsMaster’s degree in Biomolecules, Cellular Dynamics, Biochemistry, Molecular Biology, or a related field.Strong foundation in biochemistry, molecular biology, and protein science.Familiarity with bacterial protein expression and purification techniques.Basic knowledge of structural biology methods (crystallography, cryo‑EM).Ability to analyse scientific results and use computational tools for structural or biochemical studies.Capability to work independently and as part of an international, multidisciplinary team.Motivation to develop a doctoral thesis within the project framework.Good communication skills and strong proficiency in scientific English.Completion of a Master’s degree before the contract start date and formal admission to a PhD programme at a recognised Spanish university.Spanish residency (for selection through CSIC “bolsa de empleo” portal).Availability and commitment to undertake a full‑time PhD project for an estimated period of three years.Willingness to receive training in protein expression, purification, crystallography, and biophysical/enzymological techniques.Experience in studying Mur ligases and other enzymes involved in bacterial cell wall biosynthesis.Strong organisational skills, attention to detail for experimental work, data management, and documentation.Demonstrated critical, responsible, and ethical approach to scientific work.Submission of CV and motivation letter as part of the application.Excellent English; Spanish residency required.How to ApplyExpressions of interest should be accompanied by the applicant's CV and a motivation letter. Please send your application to E‑mail: ********** or contact Laura Díaz‑Sáez for more information.ContactLaura Díaz‑Sáez (contact placeholder)#J-18808-Ljbffr


  • 3-years PhD position

    hace 3 días


    madrid, España Unist A tiempo completo

    Organisation/Company Instituto de Quimica Fisica Blas Cabrera Research Field Chemistry ″ Biochemistry Researcher Profile First Stage Researcher (R1) Positions PhD Positions Country Spain Application Deadline 16 Jan 2026 - 12:00 (Europe/Madrid) Type of Contract Temporary Job Status Full-time Offer Starting Date 1 Dec 2025 Is the job funded through the EU...

  • 3-years PhD position

    hace 3 días


    Madrid, España Unist A tiempo completo

    Organisation/Company Instituto de Quimica Fisica Blas Cabrera Research Field Chemistry ″ Biochemistry Researcher Profile First Stage Researcher (R1) Positions PhD Positions Country Spain Application Deadline 16 Jan 2026 - 12:00 (Europe/Madrid) Type of Contract Temporary Job Status Full-time Offer Starting Date 1 Dec 2025 Is the job funded through the EU...

  • 3-Years Phd Position

    hace 1 día


    Madrid, Madrid, España CSIC A tiempo completo

    Organisation/Company Instituto de Quimica Fisica Blas Cabrera Research Field Chemistry '' Biochemistry Researcher Profile First Stage Researcher (R1) Positions PhD Positions Country Spain Application Deadline 16 Jan *********:00 (Europe/Madrid) Type of Contract Temporary Job Status Full-time Offer Starting Date 1 Dec **** Is the job funded through the EU...

  • 3-Years Phd Position

    hace 1 día


    madrid, España CSIC A tiempo completo

    Overview Antimicrobial Discovery Lab at Instituto de Química Física Blas Cabrera (IQF-CSIC) offers a 3‑year PhD position. The project is part of the international Open Source Antibiotics consortium, aimed at identifying inhibitors that target multiple enzymes essential for bacterial survival. Key Responsibilities Study Mur ligases (MurC, MurD, MurE,...

  • 3-Years Phd Position

    hace 2 días


    Madrid, España CSIC A tiempo completo

    OverviewDescubra exactamente qué habilidades, experiencia y cualificaciones necesitará para tener éxito en este puesto antes de enviar su solicitud a continuación.Antimicrobial Discovery Lab at Instituto de Química Física Blas Cabrera (IQF-CSIC) offers a 3‑year PhD position. The project is part of the international Open Source Antibiotics consortium,...


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