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Bioinformatics Researcher for Urban Exposome and Fetal Growth Project
hace 1 mes
About the Project
The Barcelona Institute for Global Health (ISGlobal) is seeking a researcher in bioinformatics to work on the project "urbAn exposome and fetaL growth: the roles of placental epigenoMe And function (ALMA)", funded by the Instituto de Salud Carlos III.
The project aims to evaluate the effects of the maternal urban exposome on placental epigenome and the mediating role of placental epigenome in the association between maternal urban exposome and placental function and fetal growth in 700 pregnant women.
Key Responsibilities
- Management, integration, and curation of multidimensional exposome, epigenetics, and clinical data generated in ALMA.
- Analysis of associations of exposome, epigenetics, placental function, and fetal growth.
- Design, implement, manage relational multidimensional databases.
- Perform epigenome-wide association analysis of the urban exposome with the placental methylome.
- Conduct mediation analyses between the urban exposome, methylome, and fetal growth.
- Perform annotation and functional enrichment analyses.
- Helping ALMA researchers with general quality controls, standards, and good practices to ensure quality and reproducibility.
- Provide training and support to the teams for the execution and analysis of specific analyses.
Requirements
- Master in bioinformatics, statistics, data science, or related topics.
- Previous expertise in maternal and child health research.
- Knowledge of predictive analysis, modeling, and machine learning is required to analyze complex data sets.
- Advanced bioinformatics/biostatistics skills and programming, preferably with R.
- Experience with database management software, including R.
- Experience/knowledge in analyzing complex multidimensional data using exposome methods.
- Motivated person capable of setting and meeting deadlines and delivering research outputs to the required standard.
