Protein Engineering Expert for AI-Driven Enzyme Development

hace 1 día


Barcelona, Barcelona, España Somma A tiempo completo

About Somma
Somma is a leading research institute in Barcelona, Spain, dedicated to advancing the field of synthetic biology and protein engineering through cutting-edge AI techniques.

Job Summary
We are seeking an experienced Protein Engineer to lead the experimental testing and optimization of enzymes generated by our AI models. The successful candidate will be responsible for high-throughput screening and directed evolution approaches to manage and evaluate thousands of enzymes efficiently.

About the Role
This position is critical to experimentally validate the predictions made by our AI models, providing crucial feedback to improve the models over time. As a key member of our interdisciplinary research group, you will work closely with computational scientists, experimental biologists, and biotechnologists to push the boundaries of protein engineering.

Responsibilities
* Design and execute high-throughput enzyme screening experiments using advanced techniques such as mutagenesis, cell-free systems, and/or (ultra-) high-throughput assays
* Develop protocols to screen the activity, selectivity, and thermodynamics of enzyme variants
* Automate systems for handling and screening thousands of protein variants
* Collaborate with the team to integrate computational results with experimental data to optimize enzyme design and development

Requirements
* PhD in Biochemistry, Chemistry, Molecular Biology, Biotechnology, or a related field
* 3+ years of experience in protein engineering, specifically in the testing of enzyme variants
* Wide experience in the implementation and screening of enzyme activity assays
* Familiarity with directed evolution techniques and (ultra)-high throughput techniques
* Fluency in English and strong communication skills
* Experience with robotic liquid-handling platforms for high-throughput workflows and automation is desirable but not required

What We Offer
* A highly competitive salary of approximately €60,000 - €80,000 per year, depending on experience
* Opportunities for professional growth and development in a dynamic and innovative research environment
* Collaborative and interdisciplinary team with access to state-of-the-art facilities and technologies
* Flexible working hours and a comprehensive benefits package



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