Medicinal Chemist Principal Scientist

hace 1 mes

Santiago de Compostela, La Coruña, España Celtarys A tiempo completo
Job Title: Medicinal Chemist Principal Scientist

Celtarys Research is seeking a highly skilled Medicinal Chemist Principal Scientist to join our team. As a key member of our research group, you will be responsible for the conceptualization, design, and execution of internal development projects, funded projects, and custom development of unique fluorescent probes for specific targets of interest.

Key Responsibilities:
  • Lead and coordinate the conceptualization, design, and execution of research projects for the development of fluorescent probes and other bioactive polyfunctional compounds.
  • Manage projects assigned and clients' scientific requests.
  • Learn and apply state-of-the-art enabling technologies, specifically related to molecular design and organic synthesis.
  • Collaborate with chemistry and biology department colleagues locally and throughout our collaborating research groups, companies, and entities.
  • Present ideas and results internally to discuss possible issues, solutions, and alternatives.
Requirements:
  • PhD in Medicinal Chemistry with > 2 years' experience as a Post-doc.
  • Extensive and accredited experience in medicinal chemistry basis and approaches to modify molecules' structures to improve their bioactivity.
  • Understanding of molecule/target interaction principles and modes.
  • Deep understanding of biological data related to the compounds developed to incorporate them into new designs and/or potential refinement of molecular probes leading to successful experimental outcomes.
  • Independent design of new molecules able to interact with specific targets of interest.
  • Organic synthesis: full autonomy in design and realization of multi-step synthesis for the obtention of complex molecular structures with specific restrictions in terms of stability.
  • Strong and wide knowledge of biomolecules and small molecules purification and characterization approaches.
  • Strong independence, problem-solving, troubleshooting skills, and proven ability to lead research projects.
  • Fluent in English.

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