Senior Research Scientist: X-Chromosome Inactivation and Epigenetics

hace 21 horas


Barcelona, Barcelona, España Center For Genomic Regulation A tiempo completo

About the Center for Genomic Regulation

The Center for Genomic Regulation (CRG) is a renowned international biomedical research institute in Barcelona, Spain. Our team of 400+ scientists from 44 countries works together to advance knowledge in genomics, with a focus on understanding the complex interactions between genes and their environment.

With a strong commitment to excellence in research, we have been recognized by the European Commission as an institution that adheres to the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers. We value diversity and strive to create an inclusive work environment where everyone feels welcome and empowered to contribute their best work.

The Role

We are seeking a highly skilled Postdoctoral Researcher to join our team in the Payer lab at the Tissue Engineering Facility. As part of this project, you will investigate the role of X-chromosome inactivation in oocyte development using mouse embryonic stem cells. Your expertise in advanced in vitro differentiation models and experience with mouse ESC culture will be invaluable in driving the project forward.

Your main responsibilities will include:

  • Continuing the work of Bernhard Payer on elucidating the mechanisms of epigenetic reprogramming during embryogenesis, pluripotency, and germ cell development
  • Applying a range of in vivo and in vitro model systems to interrogate X-chromosome reactivation and its link to pluripotency and germ cell development
  • Collaborating with colleagues in the Payer lab and the wider scientific community to share knowledge and best practices
  • Ensuring the efficient management of experiments and data collection to meet project deadlines

About the Lab

The Payer lab is a vibrant and dynamic research group focused on understanding the fundamental mechanisms underlying epigenetic reprogramming. Our team uses cutting-edge techniques and technologies to study the complex interactions between genes, environment, and developmental processes. By joining our lab, you will become part of a collaborative and supportive community dedicated to advancing our understanding of the human genome.

Requirements

To be successful in this role, you should have:

  • A Ph.D. in a relevant field (e.g., molecular biology, genetics, biochemistry)
  • At least 4 years of postdoctoral research experience in mouse ESC culture and advanced in vitro differentiation models
  • Excellent analytical and problem-solving skills, with the ability to design and conduct experiments independently
  • Strong communication and collaboration skills, with experience working in a team environment
  • Familiarity with CRISPR/Cas9 gene editing and other modern molecular biology techniques would be an asset

What We Offer

In addition to the opportunity to work on cutting-edge research projects, we offer a competitive salary package of approximately €50,000 - €60,000 per year, depending on your level of experience. This salary reflects the average cost of living in Barcelona and is commensurate with industry standards for a researcher of your level. You will also enjoy access to state-of-the-art facilities, including high-end microscopes, flow cytometers, and next-generation sequencing equipment. Furthermore, our institute has a flexible and efficient administration, allowing you to focus on your research without unnecessary bureaucracy.

How to Apply

If you are a motivated and experienced researcher looking for a new challenge, please submit your application, including a cover letter, CV, and contact information for three professional references. We look forward to hearing from you



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