Senior ADME

We are seeking a highly skilled Senior ADME & DMPK Scientist to join our R&D team at Almirall. As a key member of our project teams, you will provide expert ADME & DMPK support across the project lifecycle in a multidisciplinary environment.

Key Responsibilities:

1. Ensure ADME profiling, PK/PD, M&S, human dose predictions, and other related deliverables are undertaken to best practice standard for study design and decision making.
2. Selection, set-up, supervision, or incorporation of in-vitro/in-vivo models to address ADME/DMPK aspects at all stages from feasibility to candidate nomination and early clinical development.
3. Responsible for outsourcing and coordination of experimental ADME/DMPK in vitro or in vivo studies when needed.
4. Provide quality data, written reports, and presentations to ensure regular progress updates of ongoing projects.
5. Maintain an up-to-date knowledge of the relevant scientific literature as well as regulatory guidance and best practice.

Requirements:

• PhD in Pharmacy, Chemistry, Biochemistry, or Biology.
• In-depth understanding of ADME processes applied to NCEs and screening strategies from feasibility to candidate nomination.
• Good knowledge of bioanalysis and expertise in the use of LC-MS/MS platforms.
• Experience in the use of pharmacokinetic analysis software, such as Phoenix, and good understanding of PK and PK/PD principles to interpret results.
• 5+ years of experience in the field of ADME/DMPK/Bioanalysis of Small Molecule Drugs.

About Us:

Almirall is a company that values teamwork, personal leadership, and innovation. We are looking for individuals who share our values and are passionate about making a difference in the pharmaceutical industry.