Computational Biologist

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. Our institute is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

We are looking for a highly skilled Computational Biologist to join our "Evolutionary Processes Modeling" group. In this role, you will work on evolutionary and biological problems through the use and development of computational and statistical approaches. Your primary responsibilities will include analyzing data, developing models for the description of tumor DNA sequencing data, developing a computational pipeline and testing biological hypotheses.

Cancer is a genetic disease, subject to population genetics forces like mutation, selection and stochasticity. Our group is particularly interested in how the evolution and survival of cancer cell populations relies on mutation influx and in how we can identify cancer driver events from observed mutation data. To achieve this goal, we develop mathematical and computational approaches to estimate mutation rates, tumor growth dynamics and selection. By analyzing the mutational processes acting in cancer genomes, we gain insights into carcinogenic mutagens, while studying the spatial genetic heterogeneity of tumors allows us to understand the tumor mode of growth. Estimates of the strength of selection in cancer enable us to prioritize genes and non-coding regions by their disease relevance, ultimately promoting therapeutic advances.

To be successful in this position, you should have a strong background in computational biology, genomics and/or statistics. You should also have experience with programming languages such as Python, R or MATLAB. Familiarity with machine learning algorithms and data analysis tools is highly desirable. Additionally, excellent communication and collaboration skills are essential for this role.

This is a full-time position with a competitive salary of approximately €45,000 per year, commensurate with qualifications and experience. The CRG offers a dynamic and inclusive working environment, with opportunities for professional growth and development. We also provide access to state-of-the-art facilities and equipment, as well as a comprehensive benefits package including health insurance, retirement plan and paid time off.