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Postdoc Data Science Malaria Immunology Group

hace 8 meses


Barcelona, España Somm Excellence Alliance A tiempo completo

The Barcelona Institute for Global Health (ISGlobal) is a cutting-edge institute addressing global public health challenges through research, translation into policy and education. ISGlobal has a broad portfolio in communicable and non-communicable diseases including environmental and climate determinants, and applies a multidisciplinary scientific approach ranging from the molecular to the population level. Research is organized in five programs: Global Viral and Bacterial Infections; Malaria and Neglected Parasitic Diseases; Maternal Child and Reproductive Health; Environment and Health over the Lifecourse; Climate, Air Pollution, Nature and Urban Health. ISGlobal is accredited with the Severo Ochoa distinction, a seal of excellence of the Spanish Science Ministry.

Venue:
Barcelona

What We Are Looking for:
ISGlobal is seeking a Postdoctoral researcher in Data Science to work on the research projects performed by the Malaria Immunology Group. The overall goals are to identify biomarkers of disease and immunity and understand the mechanisms and mediators of protective immunity induced by infection and vaccines using multidimensional clinical, epidemiological, immunological and molecular data.

TRAINING AND EXPERIENCE /QUALIFICATIONS:
PhD in data science, biostatistics, bioinformatics, mathematics, physics, or related topics with expertise in analysis of immunology, epidemiology or biological datasets, or on biomedical sciences with data analysis and programming expertise.

Knowledge of predictive analysis, modeling and machine learning is required to analyze complex immunological data sets.

SPECIFIC REQUIREMENTS:
The purpose of the position is to ensure that complex datasets with clinical, demographic, immunological and molecular data collected in immunology studies are organized in a standard format and available for statistical analysis at ISGlobal and international collaboration centers, to facilitate completion of the Analytical Plans and perform Data Analysis. This position will also provide support in statistical analysis to other studies ongoing in the group under the supervision of the PIs. The position will require experience in data management and statistics. The position is based at ISGlobal in Barcelona.

General knowledge of the principles of biology and basic clinical science or immunology, and able to turn analytical methodology / processes into clear terms for presenting data in an understandable way.

Experience with database management software including R

Experience in programming for statistical analysis, preferably with R

Experience/knowledge in analysing complex longitudinal and multidimensional data using machine learning methods

Experience in analysis of immunological and infectious diseases data would be an asset

Motivated researcher capable of setting and meeting deadlines and delivering research outputs to the required standard

Strong organization and team-working and multi-tasking skills

Professional attitude with attention to details

Effective verbal and written communication skills

Proficiency in English (written and spoken)

Team player, yet capable of working autonomously, rational and critical thinker

Interest in public health in developing countries

KEY RESPONSIBILITIES:
Management and analysis of data generated in studies of biomarkers and immune correlates of protection against malaria and COVID-19 after infection or vaccination, as well as in other studies by the Malaria Immunology group. The studies are carried out in collaboration with multiple international research centers (Africa, Europe, USA, Australia).

Specific examples of studies that would fall under the responsibility of the new postdoc include an Horizon Europe project (WORMVACS2.0) that aims to develop new vaccines for helminths (neglected tropical diseases), in which it is required to manipulate and analyze high-dimensional data sets to down-select vaccine antigen targets and understand the host immune response to those infections.

SPECIFIC DUTIES:
Design, implement, manage relational databases (clinical, demographic and immunological data)

Participate in study design and sample selection

Preparation of statistical analysis plans

Data analysis and visualization in R and/or Python

Carry out data cleaning and quality control, including contact with international partners to solve queries

Document and archive all data for easy use in future research

Prepare data reports and manuscripts

Prepare presentation for consortium meetings

Disseminate results in international conferences

Participation in regular lab meetings and institutional seminars

AUXILIAR TASK:
This job description reflects the present requirements of the post but may evolve at any time in the future as duties and responsibilities change and/or develop providing there is appropriate consultation with the post-holder.

SKILLS:
Excellent organizational skills and able to work effectively with multidisciplinary teams, adapt to