Principal SAS Programmer Cpqp

hace 2 semanas

Barcelona, España AstraZeneca A tiempo completo

The Principal SAS Programmer is accountable for the delivery of quality of project programming work. The Principal SAS Programmer provides technical leadership either as an expert lead providing information management or through leadership of a team to influence and promote consistent approaches to data integration. Will develop and build, or act as a specialist expert within, a cross-functional multi-skilled team compromising of experts to deliver continuous improvement.

As a **Principal** **SAS** **Programmer, **you’ll play a pivotal role in channelling our pharmacometric data preparation capabilities to make a positive impact on changing patients’ lives.
- ** CPQP **(Clinical Pharmacology and Quantitative Pharmacology) is the department that oversees and delivers the pharmacokinetic and pharmacometric aspects and analysis of early and late phase clinical development. Its focus is targeting the right dose of the right drug at the right frequency via the right route to the right patient across the portfolio. The CPQP organization focuses on pharmacometric advances in small and large molecules, and other emerging technologies and drug discovery platforms across our focus areas.
- ** CPQP Programming **is the group that oversees and delivers the pharmacometric data, develops and supports modelling, analysis and operational tools along with other infrastructure framework to support internal decision making, regulatory submissions and the reporting of commercial activities across the TA portfolio of projects.

**Typical Accountabilities**
- Prepare and delivery pharmacometric data in to time and quality
- Lead pharmacometric programming deliverables to support the regulatory submissions including specification and delivery of data, output and provide response to regulatory questions.
- Oversee the quality of all deliverables, holding partners and providers accountable for the quality of their deliverable.
- Contribute to the development of best practices to improve quality, efficiency, and effectiveness
- Lead the provision of technical consulting expertise to external partners in relation to the specification and delivery of the pharmacometric data by these partners.
- Lead, develop and/or mentor a group of Programmers
- Provide strategic input and leadership to the delivery of all technical programming and information components of a project as the lead Pharmacometric programmer role
- Identify opportunities to improve the methodology and provide practical solutions for problems
- Manage junior programmers on the project(s) they lead (team of Principal, Senior, contract programmers)
- Accountable for Good Information Practice and the quality of project programming work worldwide
- Reports to Director of CPQP Programming

**Education, Qualifications, Skills and Experience**

**Essential**
- Demonstrated Leadership Capabilities
- BSc in Mathematical, Statistical, Computer Science or Life Science
- Extensive SAS programming expertise to an advanced level.
- Experience preparing pharmacometric or pharmacokinetic datasets.
- Comprehensive knowledge of technical and regulatory requirements related to the role
- Knowledge of CDASH/SDTM/ADaM CDISC standards
- Experience of Regulatory submissions
- Excellent Communication skills
- Excellent collaboration required - needs the energy to work across global & functional boundaries
- A clear demonstration of behaviours of
- Truth seeking rather than success seeking
- Agile responsiveness to scientific data
- Embracing of peer review
- Agnostic to internal-external sourcing

**Desirable**
- Other programming languages e.g. S-PLUS, R etc.

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