Computational Biology Systems Researcher
hace 2 semanas
**Context And Mission
In the Life Sciences area, we are looking for a Researcher to work in the computational systems biology approaches to simulate biological networks at different time-scales (Ponce-de-Leon et al., 2023). In particular, we are interested in the development of new approaches to the simulation of different molecular networks and of different type of cells, with emphasis on genome-scale metabolic models, Boolean regulatory networks and agent-based models, as well as the integrations of omic information to validate model predictions. These multi-scale models simulations should be able to be adapted to parallel environments to be deployed to HPC platforms at the BSC and at other HPC centres in Europe.
**Key Duties
- Co-design multi-scale simulation tools to BSC’s RISC-V and other heterogeneous architectures.
- Design, implement and deploy a set of unit tests to study the scalability and efficiency of the co-designed code and architecture.
- Implement efficient tools to simulate biological processes at different time scales through the integration of different modeling approaches (e.g. kinetic modeling, agent-based modeling, constraint-based modeling).
- Integrate multi-omics data in the model and identify actionable patient-specific targets of therapeutic interest.
**Requirements
- Education
- PhD in Computer Science, Bioinformatics or similar topic, with strong background on computational biology.
- Essential Knowledge and Professional Experience
- Proved experience on bioinformatics and computational biology.
- Strong background on computer simulation of biological processes (constraint-based, Boolean, kinetic or agent-based modelling).
- Strong programming skills, in particular on C++ and Python language.
- Administration level in Linux/Unix systems.
- Experience in HPC.
- Additional Knowledge and Professional Experience
- Experience in the preparation and presentation of scientific projects.
- Experience in reporting progress.
- Experience in mentoring/advising PhD studentes.
- Good communication skills (verbal and written) in English
- Competences
- Ability to effectively communicate technical concepts to non-experts.
- Proactive and able to take the initiative when needed.
- Creative thinking.
- Operate independently but love being part of a collaborative team.
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