Director, Translational Medicine, Oncology

hace 2 semanas


Barcelona, España AstraZeneca A tiempo completo

**Position: Director, Translational Medicine, Oncology - Breast cancer**

**Location: Cambridge, UK or Boston, US**

At **AstraZeneca**, we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.

We are seeking an Director in Oncology Translational Medicine to join a world class center for discovery and development of innovative cancer medicines. In this role you will be accountable for leading delivery of robust, scientifically-driven biomarkers in drug discovery and development programs for targeted agents in our breast cancer portfolio. You will have the opportunity to impact an industry-leading portfolio of targeted therapy programs from inception through to life cycle management for marketed drugs.

**Key Responsibilities and Accountabilities**:

- Developing biomarker strategies and ensuring delivery within oncology project teams.
- Delivering biomarkers for clinical studies based on the best available science and technologies.
- Generating disease linkage data to guide indication selection and targeted patient populations.
- Measuring target engagement reliably and quantifiably to inform clinical decisions for selecting therapeutically relevant doses and schedules.
- Understanding key cancer pathway interactions and feedback mechanisms in clinical samples to guide rational drug combinations.
- Defining novel mechanisms of resistance targeted therapies by studying tumors at relapse.

**Essential Requirements and Qualifications**:

- PhD and/or MD with extensive experience in drug development
- A minimum of 5 years’ of relevant experience
- In-depth knowledge of oncology disease area biology and translational science, with expertise in breast cancer biology and ER / AKT signaling
- Proven communication and influencing skills.
- Highly developed problem solving and risk management skills.
- Highly developed collaborative working skills.
- Ability to act as an external ambassador and to influence external organisations to enhance the image and reputation of AstraZeneca.
- Proven ability to motivate and develop others.

**So, what’s next?**

Are you already envisioning yourself joining our team? Good We can’t wait to hear from you

If you’re curious to know more, please contact Sophie Halpin, our Talent Acquisition Partner.

**Competitive remuneration and benefits apply**

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

**Where can I find out more?



  • Barcelona, España AstraZeneca A tiempo completo

    Do you feel passionate about the possibilities of great science changing lives of cancer patients? Do you have a background within oncology and/or translational research and have interest in working with antibody-drug and radio conjugates (ADCs and RC’s)? If so, this may be the role for you. We currently have an exciting opportunity for a highly motivated...


  • Barcelona, España AstraZeneca A tiempo completo

    **Head of Translational Medicine Oncology Drug Project Management** **Location: Barcelona, Spain (On-site)** The TM Oncology Drug Project Management group within Translational Medicine Oncology is accountable for providing project and portfolio management to the AZ TM Oncology portfolio to ensure successful delivery of Translational projects from...


  • Barcelona, España AstraZeneca A tiempo completo

    **About AstraZeneca** At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of...


  • Barcelona, España AstraZeneca A tiempo completo

    **Location**: Barcelona **About AstraZeneca** AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious disease. But we’re more than one of the world’s leading pharmaceutical companies. At AstraZeneca,...


  • Barcelona, España Vall d'Hebron Institute of Oncology (VHIO) A tiempo completo

    16 September 2019 **The Vall d’Hebron Institute of Oncology (VHIO) Seeks a PhD Student** **to Join our Sarcoma Translational Research Group** ***Reference**: 24/2019 ***Number of vacancies**:1 **Position description**: VHIO’s **Sarcoma Translational Research Laboratory** is a recently created research group with a highly motivating environment and...


  • Barcelona, España AstraZeneca A tiempo completo

    The Director Study Leader, Early Oncology Clinical is responsible for delivering a single or several smaller development programs or leading multiple studies or single complex/novel studies such as platform, basket, etc. The exact accountabilities will differ depending on the exact nature of the clinical program so a high degree of flexibility and autonomy...


  • Barcelona, España AstraZeneca A tiempo completo

    **_Do you have expertise in, and passion for clinical drug development? Are you looking to work at the cutting-edge, where scientific innovations and an entrepreneurial spirit are the norm? Join the team at the heart of AstraZeneca dedicated to Oncology, committed to following the science._** **About AstraZeneca** AstraZeneca is a global, science-led,...


  • Barcelona, España Vall d'Hebron Institute of Oncology (VHIO) A tiempo completo

    24 November 2015 **Reference**: **Number of vacancies**: **Offer description**: Founded in 2006 as a Private Foundation, the Vall d´Hebron Institute of Oncology (VHIO), Barcelona, Spain, is a comprehensive cancer center of excellence where its researchers and physician-scientists adopt a purely translational research model, working together as...

  • Global Development Medical Director, Late Oncology

    Encontrado en: beBee jobs ES - hace 3 semanas


    Barcelona, Barcelona, España AstraZeneca A tiempo completo

    Location: Barcelona (on-site)We are looking for a Global Development Medical Director, Late OncologyDo you have expertise in Oncology clinical drug development and passion for developing late phase clinical program strategies?Would you like to apply your expertise to impact the way cancer is treated, and make a meaningful difference to patients, in a company...


  • Barcelona, España Vall d'Hebron Institute of Oncology (VHIO) A tiempo completo

    16 November 2017 **Reference**:18/2017 **Immediate Call for Applications** **Position description**: The Vall d´Hebron Institute of Oncology´s (VHIO) recently established Radiomics Group, headed by Raquel Perez-Lopez (MD, PhD), is currently seeking to appoint an MR Research Physicist/Engineer. This post is a great opportunity to be involved in a broad...


  • Barcelona, España Vall d'Hebron Institute of Oncology (VHIO) A tiempo completo

    29 November 2018 **Application deadline**:31/01/19 **Reference**: 20/2018 **Vacancy**:1 **Job description**: **VHIO seeks a Staff Scientist in Thoracic Cancer Genomics, under the joint leadership of Enriqueta Felip and Ana Vivancos, Principal Investigators of our Thoracic Tumors and Cancer Genomics Groups, respectively.** As a leading reference in...


  • Barcelona, España Vall d'Hebron Institute of Oncology (VHIO) A tiempo completo

    3 February 2020 **The Vall d´Hebron Institute of Oncology (VHIO) Seeks a Medical Image Processing Physicist/Engineer to Join the Radiomics Group** **Reference: 17-2019** ***Immediate Call for Applications** ***Number of vacancies: 1** **Job description**: The Vall d´Hebron Institute of Oncology´s (VHIO) Radiomics Group, headed by Raquel Perez-Lopez...


  • Barcelona, España AstraZeneca A tiempo completo

    **Statistical** Science Director** - Early Oncology** **Location: Barcelona** Competitive salary and benefits Play a critical role in making our pipeline accessible to patients. AstraZeneca is a global, **science-led, patient-focused biopharmaceutical company **that focuses on the discovery, development and commercialisation of prescription medicines for...

  • Global Development Medical Director, Late Oncology

    Encontrado en: beBee S ES - hace 2 semanas


    Barcelona, España AstraZeneca A tiempo completo

    Location: Barcelona (on-site)We are looking for a Global Development Medical Director, Late OncologyDo you have expertise in Oncology clinical drug development and passion for developing late phase clinical program strategies?Would you like to apply your expertise to impact the way cancer is treated, and make a meaningful difference to patients, in a company...


  • Barcelona, España AstraZeneca A tiempo completo

    **Role Description** The Director Study Leader, Early Oncology Clinical is responsible for delivering a single or several smaller development programs or leading multiple studies or single complex/novel studies such as platform, basket, etc. The exact accountabilities will differ depending on the exact nature of the clinical program so a high degree of...


  • Barcelona, España Vall d'Hebron Institute of Oncology (VHIO) A tiempo completo

    5 March 2020 **Ref. 4/2020 Post-Doctoral position al Growth Factors Laboratory** VHIO seeks a postdoctoral researcher to join our Growth Factors Research Laboratory led by ICREA Research Professor Joaquin Arribas. The group focuses on cancer biology research with a truly translational approach. We have generated a comprehensive platform of...


  • Barcelona, España Vall d'Hebron Institute of Oncology (VHIO) A tiempo completo

    28 January 2021 **The Vall d´Hebron Institute of Oncology (VHIO) Seeks a “**Pathologist in Breast and Prostate Cancer Translational Research**”** **Reference**:Ref. 08-2021 **Application deadline**:April 20, 2021 **Number of vacancies**:1 **Job description**: (A research pathologist position is available immediately at the Molecular Oncology Group...


  • Barcelona, España Vall d'Hebron Institute of Oncology (VHIO) A tiempo completo

    7 August 2019 **The Vall d´Hebron Institute of Oncology (VHIO) Seeks a Post-Doctoral Investigator** **to Join our Chromatin Dynamics in Cancer Group** **Immediate Call for Applications** **Position description**: The appointed individual will also work on translational research projects in collaboration with oncologists to perform in vitro and in vivo...


  • Barcelona, España Vall d'Hebron Institute of Oncology (VHIO) A tiempo completo

    3 February 2021 **The Vall d´Hebron Institute of Oncology (VHIO) Seeks a “**Postdoctoral Researcher in Breast Cancer Translational Research**”** **Reference**:Ref. 06-2021 **Application deadline**:April 21, 2021 ***Number of vacancies**:1 **Job description**: **A postdoctoral position** is available immediately at the Experimental Therapeutics...


  • Barcelona, España Vall d'Hebron Institute of Oncology (VHIO) A tiempo completo

    12 May 2023 **The Vall d´Hebron Institute of Oncology (VHIO) Seeks a “**Junior** **Group Leader in Hematooncology & Immunotherapy**”** **Reference**:Ref. 48-2023 **Application deadline**:01/06/2023 **Number of vacancies**:1 **Job description**: Research themes for this position include: - Development of immune-based personalized therapeutics...