Bioinformatician

hace 2 meses


Madrid, España Empresa Reconocida A tiempo completo

.DescripciónThe Barcelona Institute for Global Health (ISGlobal) is a cutting-edge institute addressing global public health challenges through research, translation into policy and education.ISGlobal has a broad portfolio in communicable and non-communicable diseases including environmental and climate determinants, and applies a multidisciplinary scientific approach ranging from the molecular to the population level.Research is organized in the following main areas: Malaria and other Infectious Diseases, Maternal, Child and Reproductive Health, Urban Health, Child and Environmental health, and Climate & Non-Communicable Diseases. ISGlobal is accredited with the Severo Ochoa distinction, a seal of excellence of the Spanish Science Ministry.WHAT WE ARE LOOKING FOR ISGlobal is seeking a Master's level researcher in bioinformatics and data science to work on the malaria research projects performed by the Malaria Immunology Group. The overall goals are to identify molecular signatures correlating and predicting vaccine immunogenicity and protection against malaria, and to understand the mechanisms and mediators of protective immunity induced by infection and vaccines using single-cell RNAseq and CITE-Seq methods and multidimensional clinical, epidemiological, immunological and molecular data.ABOUT THE POSITION ISGlobal is seeking a researcher in bioinformatics to work on the project "Unravelling the heterogeneity and function of monocytes in vaccination and immunity to malaria (VaMonoS)", project PIDOB-I00 funded by the Ministry of Science (MCIN/AEI/// FEDER, UE). The aim of this project is to decipher the molecular, phenotypic and functional profiles of monocyte subsets associated with vaccine immunogenicity and induced protection. Ultimately, the goal of this project is to improve the health of people, particularly those responding poorly to vaccines, through the generation of novel knowledge on monocytes immunology.SPECIFIC REQUIREMENTS Bioinformatics expertise in omics analysis is essential.Previous expertise in malaria and immunology research.Knowledge of predictive analysis, modeling and machine learning is required to analyze complex immunological data sets.Advanced bioinformatics skills and programming, preferably with R.Experience with database management software including R.Experience/knowledge in analyzing complex multidimensional data using machine learning methods.Motivated researcher capable of setting and meeting deadlines and delivering research outputs to the required standard.KEY RESPONSIBILITIES Management and analysis of data generated in single-cell RNAseq, CITE-seq and ATAC-Seq experiments in relation to malaria vaccination and infection.Integration of single-cell data with immunological, epidemiological and clinical datasets.Management and analysis of other OMIC data in relation to malaria immunity.SPECIFIC DUTIES Design, implement, manage relational databases



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