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Medical Director, Early Clinical Development, Rheumatology/Clinical Immunology
hace 2 meses
Are you ready to shape and deliver the AstraZeneca Immunology pipeline? If you are a motivated drug developer, this is an excellent time to joinWho We Are In the Respiratory and Immunology Early Clinical Development team, we are investigating the drivers of key respiratory and immunology diseases, with access to pioneering science, innovative drug discovery approaches, and key collaborations with academic centers around the world. We are investigating a wide range of drug modalities – small molecules, biologics, oligonucleotides, and cell therapies – across multiple diseases with high unmet medical need.Early Clinical Development in R&I is where science meets clinical drug development with a focus upon delivering innovative, early phase clinical studies (Phase 1 – Phase 2b), while collaborating closely with our late phase clinical development colleagues who guide our phase 3 clinical studies. We are a diverse team of physicians and clinical scientists who collaborate with scientists and translational medicine colleagues to define our early phase clinical development strategies, design innovative phase 1-2b clinical trials, develop and validate new clinical endpoints, and translate scientific ideas to proof-of-concept studies in targeted patient populations.What You Will Do As the Medical Director, you will provide medical and scientific input to preclinical and clinical stage assets focused on Rheumatology/Clinical Immunology. You will take responsibility for clinical development in cross-functional teams to support early phase clinical development activities. These include the creation of overall clinical development plans and clinical study design, as well as writing protocols, key study and health authority documentation, medical monitoring, and ensuring timely delivery of studies, all in close collaboration with internal and external partners and clinical research organizations.Rheumatology experience is a must and will ideally include clinical development experience in relevant indications, e.G., systemic lupus erythematosus (SLE), Rheumatoid Arthritis (RA), Sjogrens, or Systemic Sclerosis. The successful candidate will thrive in a fast-paced, proactive can-do culture, and be a strong communicator and collaborator.Responsible for the design, delivery, and interpretation of clinical studies ensuring the ethical and scientific integrity of the plans, studies, and product in compliance with GCP.Provide guidance in the medical strategy and clinical/disease expertise to Research, Translational Medicine, Early and Late-stage Clinical Development, and Commercial colleagues as part of cross-functional teams.Closely follow medical developments within the autoimmune/inflammatory diseases and disseminate new information within Clinical Development and the wider organization to transform trends and emerging data into agile and innovative clinical plans.#J-18808-Ljbffr
